Early Functional Outcomes After Robot-Assisted Radical Prostatectomy: A Prospective Comparison of the HOOD Technique Versus Standard Anterior Reconstruction
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 200
- 试验地点
- 1
- 主要终点
- Functional outcomes
研究概览
简要总结
This prospective, non-randomized cohort study included consecutive patients undergoing robotic-assisted laparoscopic radical prostatectomy (RARP) between January 2024 and January 2026 following ethics committee approval. Patients with clinically localized prostate cancer eligible for bilateral nerve-sparing surgery were enrolled. Two surgical techniques-anterior-posterior reconstruction (APR) and the HOOD technique-were compared. All procedures were performed by a single high-volume surgeon at a tertiary referral center. The primary endpoint was early urinary continence recovery, assessed at catheter removal and at 3, 6, and 12 weeks postoperatively. Secondary outcomes included postoperative complications, positive surgical margin rates, and early oncological outcomes.
研究设计
- 研究类型
- Interventional
- 分配方式
- Non Randomized
- 干预模型
- Parallel
- 主要目的
- Other
- 盲法
- None
入排标准
- 年龄范围
- 40 Years 至 75 Years（Adult, Older Adult）
- 性别
- Male
- 接受健康志愿者
- 否
入选标准
- •life expectancy >10 years,
- •clinically organ confined disease (cT1-cT2),
- •biopsy ISUP GG ≤3,
- •total serum prostate-specific antigen (PSA) ≤10 ng/ml
- •normal preoperative continence and potency
排除标准
- •high risk prosatate cancer
- •M1 prostate cancer (according to preoperative GA68 PSMA PET CT)
- •pre-existing urinary incontinence,
- •previous prostatic, urethral, bladder neck surgery
- •neoadjuvant therapy
- •prior pelvic radiotherapy
研究组 & 干预措施
HOOD technique
干预措施: Prostatectomy with HOOD techinque (Procedure)
Anterior-Posterior reconstruction
干预措施: Prostatectomy with anterior-posterior renconstruciton (Procedure)
结局指标
主要结局
Functional outcomes
时间窗: 3 weeks , 6 weeks and 12 weeks after surgery.
The Urinary continance recovery rates at the catheter removal, and subsequently at 3 weeks , 6 weeks and 12 weeks after surgery.
次要结局
未报告次要终点
研究者
Araz Musaev
Dr
Ankara University