Quantitative detection of periodontopathogens in gingival sulcus fluid by real-time PCR
- Conditions
- Diseases of the digestive system
- Registration Number
- KCT0009168
- Lead Sponsor
- Gachon University
- Brief Summary
Among all other strains within the same group, the strains that demonstrated significant static correlations as indicators of influence were T. denticola from the red complex and F. nucleatum from the orange complex. Particularly, P. nigrescens from the orange complex exhibited significant static correlations with all strains classified in the red and green complexes, suggesting its role as a connecting link between complexes. The quantity of pathogenic microorganisms based on individual characteristics showed differences in orange complex E. nodatum based on age and alcohol consumption in the BGI-DL/MB group, differences in green complex E. corrodens based on hypertension and diabetes in the BGI-DL/LB group, and differences in P. gingivalis from the red complex based on stress perception in the BGI-H group and P. nigrescens from the orange complex based on stress perception in the BGI-LB group.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- All
- Target Recruitment
- 60
Individuals aged 20 and above who have not received periodontal treatment within the last three months, do not have a history of antibiotic use within the last three months, and have no history of pregnancy, breastfeeding, or oral
contraceptive intake.
Participants with a history of periodontal treatment, antibiotic use, and oral contraceptive intake within the last three months, as well as those who were pregnant, breastfeeding, or in conditions that could affect microbial composition, were included.
Study & Design
- Study Type
- Observational Study
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Differences in the Quantity of Pathogenic Microorganisms Among BGI Index Groups.
- Secondary Outcome Measures
Name Time Method Differences in the Occurrence Rate of Pathogenic Microorganisms Between Healthy Control Group and Periodontitis Case Group.