Pleural Infection Trial (PIT-1)

Completed

• Conditions: Pleural infection; Respiratory; Pyothorax with fistula

• Registration Number: ISRCTN21646859
• Lead Sponsor: orth Bristol NHS Trust (UK)

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Start: 2012-05-22
• Last Update Posted: 17 October 2016

Recruitment & Eligibility

• Status: Completed
• Sex: All
• Target Recruitment: 40

Inclusion Criteria

1. Clinical presentation consistent with pleural infection requiring chest tube drainage
2. Pleural fluid is:
2.1. Purulent
2.2. Gram stain or culture positive
2.3. pH >7.2

Exclusion Criteria

1. Inability to give informed written consent
2. Pregnancy or lactation
3. Age < 18 years
4. Previous thoracic surgery for pleural infection
5. Drain size > 14F already placed or drain placed >72 hours ago

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Change in volume of pleural fluid between 12 - 72 hours and 4-9 days post chest drain placement (before and after 9 irrigations/flushes) as assessed on CT scan with volumetric reporting.