Ultrasound Elastography in Differentiation of Endometriomas and Hemorrhagic Ovarian Cysts
试验速览
- 阶段
- 不适用
- 入组人数
- 33
- 试验地点
- 2
- 主要终点
- evalute the value of ultrasound elastography in differentiation in endometriomas and ovarian hemorrhagic cysts
研究概览
简要总结
To investigate the value of ultrasound elastography in differentiating endometriomas from ovarian hemorrhagic cysts
详细描述
The participants will be subjected to:
- Personal, Obstetric and gynecological History taking.
- Clinical examination.
- B-mode ultrasonography was performed to characterize the adnexal masses morphologically.
- Color Doppler ultrasound.
- Grayscale and elastographic ultrasound examination, which will be done using acoustic radiation force impulse (ARFI) imaging with virtual touch quantification (VTQ). Five consecutive measurements were recorded for each lesion from the region identified as the region of interest (ROI) and the median of these measurements was recorded as the shear wave velocity (SWV) value of the lesion. In virtual touch quantification (VTQ) the shear wave speed is expressed in m/s. Only numerical results will be taken into consideration.
. Realtime elastographic and B-mode images simultaneously will appear as a two-panel image. Elastogram appeared in the region of interest (ROI) box to determine the target ovarian lesion and surrounding tissue, then elasticity colour code will be classified in 5 patterns : pattern 1, an absent or a very small hard area; pattern 2, hard area 45 per cent; pattern 4, peripheral hard and central soft areas; pattern 5, hard area occupying entire solid component with or without soft rim. Strain index will be analyzed, which will be obtained by comparing the absolute strain value of solid component of ovarian cyst with that of surrounding soft tissue.
- The invistigator will reevaluate the lesions 4 weeks after the initial assessment to see the possible changes in the size and/or configuration of the lesions with B-mode and elastographic ultrasonography.
- Lesion will be evaluated as endometriomas and referred for surgery when shows no significant changes in size and configuration.
- Hemorrhagic cyst diagnosis will be made if the lesion had resolved on follow-up.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Diagnostic
- 盲法
- Single (Investigator)
盲法说明
Single investigator
入排标准
- 年龄范围
- 18 Years 至 52 Years(Adult)
- 性别
- Female
- 接受健康志愿者
- 是
入选标准
- •Patient suspected to have endometrioma or hemorrhagic ovarian cysts.
排除标准
- •Simple cysts which were defined as a sonolucent thin-walled (<3 mm thick) cyst larger than 3 cm in diameter without septations or papillary projections [12].
- •Hemorrhagic cysts containing septations or mural nodules with detectable flow on Doppler ultrasonography
结局指标
主要结局
evalute the value of ultrasound elastography in differentiation in endometriomas and ovarian hemorrhagic cysts
时间窗: 4 weeks
the cut of value of strain ratio in diagnosis of endometrioma and ovarian hemorrhagic cyst
次要结局
未报告次要终点
