Effects of Lower Body Positive Pressure in People With Knee Osteoarthritis
- Conditions
- Knee Osteoarthritis
- Interventions
- Other: Exercise
- Registration Number
- NCT05585099
- Lead Sponsor
- Qassim University
- Brief Summary
The goal of this clinical trial is to compare effects of retro walking exercise versus forward walking using lower body positive pressure on knee pain, physical function, and quadriceps muscle strength in people with mild to moderate knee OA. The secondary aim is to compare effects of retro walking exercise versus forward walking using lower body positive pressure on mobility function, balance, and self-reported health outcomes in people with mild to moderate knee OA. The main questions it aims to answer are:
* Does retro walking exercise improve knee pain, physical function and Quadriceps muscle strength compared to forward walking exercise using lower body positive pressure in people with mild to moderate knee osteoarthritis?
* Does retro walking exercise improve Mobility function, balance, and self-reported health outcomes compared to forward walking exercise using lower body positive pressure in people with mild to moderate knee osteoarthritis?
Participants will walk (retro versus forward) on a lower body positive pressure treadmill.
If there is a comparison group: Researchers will compare \[retro walking compares to forward walking\] to see if \[improve in knee pain, physical function, and quadriceps muscles strength\]
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- RECRUITING
- Sex
- All
- Target Recruitment
- 26
- Mild to moderate knee osteoarthritis
- Edge bigger or equal 40 years
- Knee pain reported by participants in the past 30 days
- One or both knees osteoarthritis graded with Kellgren & Lawrence grade 1 - 3
- If they didn't meet the inclusion criteria
- History of hip, knee or ankle injury or surgery within the last year
- Kellgren & Lawrence grade > 3 of severe knee OA
- Diagnosed with rheumatoid arthritis
- History of knee injection with any medicine that reduce pain within the last year
- History of other medical condition that would disturb normal walking function
- Receive physical therapy in the last three months
- Pregnant
- Other conditions that are Contra indication to lower body positive pressure.
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- PARALLEL
- Arm && Interventions
Group Intervention Description Control Exercise Participants will walk in forward walking exercise on lower body positive pressure treadmill. Experimental Exercise Participants will walk in retro walking exercise on lower body positive pressure treadmill.
- Primary Outcome Measures
Name Time Method Thigh muscle strength test Change from baseline thigh muscle strength at 6 weeks. A Biodex isokinetic dynamometer (Model 4Pro) connected to a computer will be used to assess bilateral knee's flexor and extensor isometric muscle strength.
Numeric pain rating scale Change from baseline pain at 6 weeks The NPRS is an 11-point scale with "0" representing "no pain" and "10" representing "most imaginable pain" used to assess pain intensity.
Knee injury and osteoarthritis outcome score (KOOS) Change from baseline pain, symptoms, and level of disability at 6 weeks. The KOOS is a self-reported, knee-specific questionnaire that is aimed to measure knee pain, symptoms, and level of disability during the last week.
- Secondary Outcome Measures
Name Time Method Functional reach test Change from baseline static balance at six weeks FRT used to assess participant's stability and balance by measuring the maximum distance participant can reach forward while standing in fixed position.
Patient Health Questionnaire -9 Change from baseline depression at six week PHQ-9 is an instrument to evaluate depression symptoms among different populations.
10-Meter Walk Test Change from baseline walking speed at six weeks The 10-MWT evaluates walking speed over a short duration with or without an assistive device.
Rapid Assessment of Physical Activity Change from baseline physical activity at six week RAPA is a 9-items, self-reported questionnaire measures the levels of physical activity of adult older than 50 years.
4 square step test Change from baseline dynamic balance and coordination at six weeks The test is designed to assess dynamic balance and coordination.
6 minute walk test Change from baseline aerobic capacity and endurance at six week 6MWT assesses the distance walked over 6 minutes as a test of aerobic capacity and endurance.
Five times sit to stand test Change from baseline balance at 6 weeks. The FTSST is used to assess lower extremity strength and balance and is an indicator of postural control.
3-M Backward Walk Test Change from baseline backward walking at six weeks. Patients will be instructed to walk backwards when the assessor says "go" and stop when the participant pass the end line colored tape. The participant will be allowed to look back.
Timed up and go test Change from baseline Functional mobility at six weeks. The TUG assesses functional mobility by assessing an individual's ability to stand up, walk 3 meters at a comfortable pace, turn 180 degrees, walk back 3 meters, and sit down
Medical Outcomes Study Short Form 12 (SF-12) Change from baseline quality of life at six weeks It is a health survey that evaluates health related quality of life in a clinical practice and research purpose
Trial Locations
- Locations (2)
Qassim university medical city
🇸🇦Buraydah, Almuledia, Saudi Arabia
Medical City in Qassim University
🇸🇦Buraidah, Saudi Arabia