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临床试验/NCT05647642
NCT05647642招募中不适用

The Effect of Premedication Methods to be Applied to Prevent Preoperative Anxiety in Patients Who Will be Operated for Breast Cancer, on Postoperative Anxiety and Pain

Dr Abdurrahman Yurtaslan Ankara Oncology Training and Research Hospital1 个研究点 分布在 1 个国家目标入组 80 人开始时间: 2022年10月16日最近更新:
适应症
干预措施
相关药物

试验速览

阶段
不适用
状态
招募中
发起方
入组人数
80
试验地点
1
主要终点
effect of premedication on postoperative pain and anxiety scores

研究概览

简要总结

In this study, it was investigated whether the premedication drug administered before the surgery had an effect on postoperative pain and anxiety scores in female patients under the age of 65 who will undergo breast cancer surgery.

详细描述

In this study, it was investigated whether the premedication drug administered before the surgery had an effect on postoperative pain and anxiety scores in female patients under the age of 65 who will undergo breast cancer surgery. The STAI-1(State Trait Anxiety İnventory ) form and APAIS (Amsterdam Preoperative Anxiety and İnformation Scale) scale were filled in for all preoperative patients. Afterwards, the patients were treated with either midazolam or dexmedetothymidine, depending on the anesthesiologist's preference. After administration, he was taken to surgery. As intraoperative analgesics, 2 mg/kg tramadol and 15 mg/kg paracetamol were administered to all patients. postoperative recovery time (aldrete 10), 1., 2.,6.,12.,24. VAS score, postoperative nausea-vomiting scale, STAI-1(State Trait Anxiety İnventory ) form, first need time if postoperative analgesic was needed, and 24-hour total analgesic consumption were recorded. It was aimed to examine the effects of different premedications on postoperative pain and anxiety

研究设计

研究类型
Observational
观察模型
Cohort
时间视角
Prospective

入排标准

年龄范围
18 Years 至 65 Years(Adult, Older Adult)
性别
Female
接受健康志愿者

入选标准

  • ASA 1-2-3
  • 18-65 aged
  • Female patients

排除标准

  • Under 18 years old and over 65 years old
  • Having a history of cerebrovascular disease illiteracy
  • Have visual and auditory problems İnability to cooperate with cognitive function test
  • Having emergency surgery
  • Those who are unable to read, understand and sign the consent form
  • Patients deemed unsuitable by the investigator

研究组 & 干预措施

low dose midazolam

0,025 mg/kg Midazolam

干预措施: Precedex and dormicum (Drug)

high dose midazolam

0,05 mg/kg Midazolam

干预措施: Precedex and dormicum (Drug)

low dose dexmedetothymidine

0.5 mg/kg dexmedetothymidine 10 minute infusion

干预措施: Precedex and dormicum (Drug)

high dose dexmedetothymidine

1mg/kg dexmedetothymidine 10 minute infusion

干预措施: Precedex and dormicum (Drug)

结局指标

主要结局

effect of premedication on postoperative pain and anxiety scores

时间窗: November 2022-December 2022

次要结局

未报告次要终点

研究者

发起方
Dr Abdurrahman Yurtaslan Ankara Oncology Training and Research Hospital
申办方类型
Other
责任方
Principal Investigator
主要研究者

Seyda ARI

Doctor

Dr Abdurrahman Yurtaslan Ankara Oncology Training and Research Hospital

研究点 (1)

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