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Clinical Trials/NCT05647642
NCT05647642
Recruiting
Not Applicable

The Effect of Premedication Methods to be Applied to Prevent Preoperative Anxiety in Patients Who Will be Operated for Breast Cancer, on Postoperative Anxiety and Pain

Dr Abdurrahman Yurtaslan Ankara Oncology Training and Research Hospital1 site in 1 country80 target enrollmentOctober 16, 2022

Overview

Phase
Not Applicable
Intervention
Precedex and dormicum
Conditions
Female Patients Under the Age of 65 Who Will Undergo Breast Cancer Surgery
Sponsor
Dr Abdurrahman Yurtaslan Ankara Oncology Training and Research Hospital
Enrollment
80
Locations
1
Primary Endpoint
effect of premedication on postoperative pain and anxiety scores
Status
Recruiting
Last Updated
3 years ago

Overview

Brief Summary

In this study, it was investigated whether the premedication drug administered before the surgery had an effect on postoperative pain and anxiety scores in female patients under the age of 65 who will undergo breast cancer surgery.

Detailed Description

In this study, it was investigated whether the premedication drug administered before the surgery had an effect on postoperative pain and anxiety scores in female patients under the age of 65 who will undergo breast cancer surgery. The STAI-1(State Trait Anxiety İnventory ) form and APAIS (Amsterdam Preoperative Anxiety and İnformation Scale) scale were filled in for all preoperative patients. Afterwards, the patients were treated with either midazolam or dexmedetothymidine, depending on the anesthesiologist's preference. After administration, he was taken to surgery. As intraoperative analgesics, 2 mg/kg tramadol and 15 mg/kg paracetamol were administered to all patients. postoperative recovery time (aldrete 10), 1., 2.,6.,12.,24. VAS score, postoperative nausea-vomiting scale, STAI-1(State Trait Anxiety İnventory ) form, first need time if postoperative analgesic was needed, and 24-hour total analgesic consumption were recorded. It was aimed to examine the effects of different premedications on postoperative pain and anxiety

Registry
clinicaltrials.gov
Start Date
October 16, 2022
End Date
January 30, 2023
Last Updated
3 years ago
Study Type
Observational
Sex
Female

Investigators

Sponsor
Dr Abdurrahman Yurtaslan Ankara Oncology Training and Research Hospital
Responsible Party
Principal Investigator
Principal Investigator

Seyda ARI

Doctor

Dr Abdurrahman Yurtaslan Ankara Oncology Training and Research Hospital

Eligibility Criteria

Inclusion Criteria

  • ASA 1-2-3
  • 18-65 aged
  • Female patients

Exclusion Criteria

  • Under 18 years old and over 65 years old
  • Having a history of cerebrovascular disease illiteracy
  • Have visual and auditory problems İnability to cooperate with cognitive function test
  • Having emergency surgery
  • Those who are unable to read, understand and sign the consent form
  • Patients deemed unsuitable by the investigator

Arms & Interventions

low dose midazolam

0,025 mg/kg Midazolam

Intervention: Precedex and dormicum

high dose midazolam

0,05 mg/kg Midazolam

Intervention: Precedex and dormicum

low dose dexmedetothymidine

0.5 mg/kg dexmedetothymidine 10 minute infusion

Intervention: Precedex and dormicum

high dose dexmedetothymidine

1mg/kg dexmedetothymidine 10 minute infusion

Intervention: Precedex and dormicum

Outcomes

Primary Outcomes

effect of premedication on postoperative pain and anxiety scores

Time Frame: November 2022-December 2022

Study Sites (1)

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