Rotational Thromboelastometry (ROTEM)-guided blood product in patients with cirrhosis undergoing invasiveprocedures

Not Applicable

Recruiting

• Conditions: iver cirrhosis; Coagulopathy; Liver cirrhosis; Oral and Gastrointestinal - Other diseases of the mouth, teeth, oesophagus, digestive system including liver and colon; Surgery - Other surgery; Blood - Clotting disorders

• Registration Number: ACTRN12619000644167
• Lead Sponsor: Alfred Health

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2019-04-30
• Last Update Posted: 29 August 2022

Recruitment & Eligibility

• Status: Recruiting
• Sex: All
• Target Recruitment: 50

Inclusion Criteria

Males and females aged 18 years or older
-Cirrhosis
-Planned for an invasive procedure
-Coagulopathic on the basis of conventional coagulation tests
-Able to give informed consent

Exclusion Criteria

-Persons under 18 years of age
-Inability or unwillingness to give informed consent
-Coagulation disorders (other than those relating to liver disease)
-Patients on anticoagulant medications (e.g. warfarin, enoxaparin, rivaroxaban, dabigatran, apixiban).
-Patients on anti-platelet aggregation agents other than aspirin (eg. clopidogrel, ticagrelor)
-Patients in whom it is difficult to obtain blood samples due to venous access difficulties
-Active malignancy
-Patients who have received FFP, platelet transfusion, cryoprecipitate in the week prior
- Patients with stage 4 or 5 chronic kidney disease
-Patients receiving renal replacement therapy
-Patients with active sepsis

Study & Design

• Study Type: Interventional
• Study Design: Not specified