Efficacy and optimized dosage of botulinum toxin type A injection for treatment of Acne vulgaris, enlarged pore, and oiliness: A randomized placebo-controlled trial

Srinakharinwirot University0 个研究点目标入组 75 人开始时间: 2023年10月25日最近更新: 2024年8月19日

适应症

试验速览

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•1. Healthy patients age 18 to 45 years old, 2. Patients with moderate acne vulgaris according to Clinical practice guideline of acne of Dermatological society of Thailand, 3. Consent to study

•1. Received a forehead injection of botulinum toxin within 6 months before the study, 2. Received a forehead injection of hyaluronic acid (HA), biostimulator, or mesotherapy within 6 months before the study, 3. Received the systemic treatments before the study (3.1 Anti-inflammatory drugs or drugs that have an effect on the treatment of acnes such as oral corticosteroids, oral antibiotics, oral contraceptive pills or oral zinc supplement within 1 month before the study, 3.2 Drugs in retinoid group such as oral isotretinoin within 3 months before the study), 4. Received the topical drugs for acne such as topical antibiotics, topical retinoids, or topical corticosteroids within 1 month before the study, 5. History of botulinum toxin A allergy or allergy to any ingredients in botulinum toxin type A, 6. History of botulinum toxin A resistance, 7. History of neuromuscular disorders such as myasthenia gravis, Lambert-Eaton syndrome, 8. Current or active facial bacterial, fungal, or viral infection, 9. Pregnancy or lactation, 10. Cannot follow up throughout the study period

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