Measurement precision, accuracy and user performance evaluation in subjects with and without diabetes, a non-invasive blood glucose measurement device

Diabetes is the body’s inability to produce insulin. If undiagnosed or untreated it may lead to several health complications. Monitoring an individual’s glucose level is essential to managing it effectively. Present clinical methods are invasive. The optical approach is the most promising technology for non-invasive glucose monitoring. We have developed such an optical system with dual near-infrared wavelengths that have affinity for the glucose molecule. A clinical trial is required to validate the developed device against the gold standard.

At present, invasive blood glucose detection technology is mainstream, convenient, and practical, so both hospitals and household glucometers adopt the method of blood sampling first and then analyzing it in vitro for blood glucose measurement.

The non-invasive diagnosis of diabetes mellitus can be achieved by the optical system. The optical system consists of dual LEDs and a photodetector in a 3D enclosure. With the measurement site as the index finger, the change in the intensity of the reflected light from the finger is measured. The data is acquired from the patient with the finger placed on the optical system through a personal computer.

The device’s easy-to-use design and painless measurement method are intended to enhance the patient’s quality of life and increase compliance, which will improve diabetes management.