Risk Factors of Recovery Room Delirium After Elective Non-cardiovascular Surgery

Completed

• Conditions: Delirium

• Registration Number: NCT00991913
• Lead Sponsor: Huazhong University of Science and Technology

Brief Summary

Despite recent advances in postoperative delirium research, the proportion of patients with postoperative delirium is still high ranging between 20-80%. Although postoperative delirium is a frequent complication and is associated with the need for more inpatient hospital care and longer length of hospital stay, little is known about risk factors for recovery room delirium (RRD) occurred in postanaesthesia care unit. The aim of the study was to determine pre- and intraoperative risk factors for the development of RRD among patients undergoing non cardiovascular surgery.

Detailed Description

Recovery room delirium (RRD) defined as delirium occurred in PACU was diagnosed according to CAM-ICU criteria. Pre-, intra-, and postoperative data of patients undergoing elective non cardiovascular surgery were prospectively collected, univariate and multivariate logistic regression were performed to find the risk factors related to postoperative delirium.

Study Timeline

• Study First Submitted: 2009-10-07
• Study First Submitted QC: 2009-10-07
• Study First Posted: 2009-10-08
• Study Start: 2010-06-01
• Primary Completion: 2010-06-30
• Study Completion: 2010-06-30
• Status Verified: 2020-07
• Last Update Submitted: 2020-07-20
• Last Update Posted: 2020-07-21

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 228

Inclusion Criteria

• elective non-cardiovascular surgery
• general anesthesia

Exclusion Criteria

• under 18yr of age
• under regional anaesthesia
• refused to sign consent form
• history of substance dependence
• underwent neurosurgery
• history of primary neurologic diseases
• stayed less than 10min in PACU
• received general anaesthesia but recovered in locations outside the recovery room

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
The incidence of delirium in post anesthesia care unit (PACU) determined by confusion assessment method (CAM) -ICU criteria	at 1 hour after operation

Secondary Outcome Measures

Name	Time	Method
Pulse Oximeter Oxygen Saturation (SpO2) in PACU	every 10 mins
Hospital-length of stay	up to 6 months
Total health care fees	up to 6 months
heart rate in PACU	every 10 mins	heart rate was recorded every 10 min during PACU stay, maximal and minimal heart rate were collected for analysis

Trial Locations

Locations (1)

Department of Anaesthesiology, Tongji Hospital of Tongji Medical College, Huazhong University of Science and Technology; 🇨🇳 Wuhan, Hubei, China