The Influence of Local Infiltration Analgesia by Catheter in Postoperative Control Pain After Total Hip Replacement
Overview
- Phase
- Phase 4
- Intervention
- Bupivacaine hydrochloride
- Conditions
- Musculoskeletal Pain
- Sponsor
- Parc de Salut Mar
- Enrollment
- 100
- Locations
- 1
- Primary Endpoint
- Change in pain measured with a visual analog scale
- Status
- Completed
- Last Updated
- 9 years ago
Overview
Brief Summary
A randomized double-blind clinical trial was performed. There were 4 groups according to catheter placement and infusion constituents: 1) Intraarticular catheter + anesthetics; 2) Intraarticular catheter +placebo; 3) Subfascial catheter + anesthetics; 4) Subfascial catheter + placebo. The anesthetics infusion contained bupivacaine (bolus + continuous perfusion up to 36 hours). The placebo solution consisted in physiological serum (bolus + continuous perfusion up to 36 hours). Randomization was performed in the hospital pharmacy and the surgeon kept out the surgical field when the resident placed the catheter. The same conventional analgesic schedule was prescribed to all patients: PCA (patient controlled analgesia) + paracetamol 1g/6h + dexketoprofen 50mg/12h. The pain was evaluated by means of PCA (patient controlled analgesia) shots and the VAS (visual analog scale). Side effects, time to start rehabilitation and time to discharge were also analyzed. A statistical analysis was performed to compare all this variables between the 4 groups (SPSS 18.0).
Investigators
Daniel Pérez Prieto
MD
Parc de Salut Mar
Eligibility Criteria
Inclusion Criteria
- •Primary total Hip Replacement
Exclusion Criteria
- •Allergic to Bupivacaine
Arms & Interventions
Intraarticular Catheter with anesthesic
Intraarticular infusion with Bupivacaine Hydrochloride
Intervention: Bupivacaine hydrochloride
Intraarticular Physiological Saline
Infusion of Physiological Saline \[Flebobag Salina Fisiologica Grifols 0.9%\] Sterile Solution by intraarticular catheter
Intervention: Physiological Saline
Perifascial Catheter with anesthesic
Perifascial infusion with Bupivacaine Hydrochloride
Intervention: Bupivacaine hydrochloride
Perifascial Physiological Saline
Infusion of Physiological Saline \[Flebobag Salina Fisiologica Grifols 0.9%\] Sterile Solution by Perifascial catheter
Intervention: Physiological Saline
Outcomes
Primary Outcomes
Change in pain measured with a visual analog scale
Time Frame: 36 hours
Visual analog pain scale score every eight hours for 36 hours postoperatively