Comparative effectiveness of chlorhexidine gluconate versus normal saline in post oral cavity surgery wound healing of oral cavity cancer patients

Phase 3

Recruiting

• Conditions: wound healing; oral hygiene; 0.12% chlorhexidine gluconate (c-20); Normal saline; post oral cavity surgery in oral cavity cancer patients; Oral cavity surgery; oral cavity cancer

• Registration Number: TCTR20210826002
• Lead Sponsor: Ratrchadapiseksompoch fund

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Start: 2021-08-26
• Study Completion: 2022-06-30
• Last Update Posted: 19 August 2024

Recruitment & Eligibility

• Status: Recruiting
• Sex: All
• Target Recruitment: 50

Inclusion Criteria

oral cavity cancer patients
oral cavity surgery that has a primary suture and size of the wound more than 2 cm.

Exclusion Criteria

American Society of Anesthesiologist(ASA) physical status classification score more than 3
a patient who has the oral mucosal disease
a patient who has severe ischemic heart disease, renal disease), connective tissue disease, Liver disease, HIV, Diabetics Mellitus poor control
a patient who has coagulation problem or bleeding disorders (Platelet <50,000 or PT, APTT> 1.5x normal control or INR>1.5)
allergy to chlorhexidine

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Comparative effectiveness of chlorhexidine gluconate versus normal saline in post oral cavity surgery wound healing of oral cavity cancer patients at 3, 14 days after surgery Wound healing : IPR wound healing scale

Secondary Outcome Measures

Name	Time	Method
Comparative complication of chlorhexidine gluconate versus normal saline in post oral cavity surgery wound healing of oral cavity cancer patients at 3, 14 days after surgery Pain score (VAS) Side effect : irritation/allergy/hypogeusia/brown straining of the dentition