Evaluation of efficacy of erector spinae plane block performed with two different bupivacaine concentrations on postoperative analgesia after mastectomy surgery

Not Applicable

Completed

• Conditions: breast cancer; postoperative pain; Cancer - Breast; Anaesthesiology - Pain management

• Registration Number: ACTRN12618001334291
• Lead Sponsor: Basak ALTIPARMAK

Brief Summary

In the current study, ultrasound-guided ESP block performed using two concentrations of bupivacaine (0.25% and 0.375%) provided effective analgesia after radical mastectomy surgery. However, the ESP block at the higher concentration of bupivacaine reduced postoperative tramadol consumption more significantly than the lower concentration of bupivacaine. In addition, the NRS scores of group I were significantly lower than group II. The intraoperative fentanyl requirements of the patients in the two groups were similar.

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2018-08-08
• Study Completion: 2018-09-11
• Last Update Posted: 15 July 2019

Recruitment & Eligibility

• Status: Completed
• Sex: Female
• Target Recruitment: 42

Inclusion Criteria

Patients with ASA physical status I-III, between 18-70 years old ,scheduled for an elective unilateral radical mastectomy with axillary lymph node dissection

Exclusion Criteria

The patients with coagulation disorder, known allergy to local anesthetics, infection at the injection site, history of previous mastectomy, advanced hepatic or renal failure or chronic opioid consumption

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
To assess the postoperative opioid consumption in the first 24 hours by calculating the tramadol dose administered by patient controlled analgesia device [Postoperative 24th hour]

Secondary Outcome Measures

Name	Time	Method
To assess pain scores of the patients by using 11-points numerical rating scale (NRS) at the postoperative 15th minute, 30th minute, 60th minute (secondary outcome), 12th hour and 24th hour[Postoperative 15th minute, 30th minute, 60th minute (secondary outcome), 12th hour and 24th hour];To assess intraoperative fentanyl consumption by using data-linkage to surgical records[At the end of each surgery]