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Clinical Trials/CTRI/2025/01/079167
CTRI/2025/01/079167
Completed
Not Applicable

To evaluate and compare the in-vivo safety and efficacy of Skin Care Formulation verses Untreated Control in terms of skin moisturization and skin barrier function on healthy female subjects

Alembic Pharmaceuticals Ltd.1 site in 1 country33 target enrollmentStarted: February 1, 2025Last updated:

Overview

Phase
Not Applicable
Status
Completed
Enrollment
33
Locations
1
Primary Endpoint
skin moisturization and skin barrier function

Overview

Brief Summary

OBJECTIVE 

The objective of this study will be to evaluate and compare the in-vivo safety and efficacy of Skin Care Formulation verses Untreated Control in terms of skin moisturization and skin barrier function on healthy female subjects for product.

Test Product: Oryza Acne Cream: Product A

Techniques: The evaluation is performed using: 1) Subject Self Evaluation, 2) Dermatological Evaluation: Safety, 3) Corneometry and 4) Tewametry

Total duration of the study: 72 hours following the first application of the product.

Kinetics: T0, T+30 Minutes, T+24 hours, T+48 hours & T+72 Hours after product application

POPULATION: 33 female subjects will be selected for the study.

The subjects selected for this study are healthy female subject, aged between 18 and 40 years old, having dry skin on forearms

Study Design

Study Type
Interventional
Allocation
Randomized
Masking
Participant Blinded

Eligibility Criteria

Ages
18.00 Year(s) to 40.00 Year(s) (—)
Sex
Female

Inclusion Criteria

  • 1.Indian female subjects 2.Healthy subjects 3.Skin is healthy on the studied anatomic unit 4.Subject having dry skin on forearms.

Exclusion Criteria

  • Being pregnant or breastfeeding or having stopped to breastfeed in the past three months.
  • Having refused to give his/her assent by not signing the consent form and Informed consent form
  • Taking part in another study liable to interfere with this study
  • Being known diabetic case
  • Known asthma case
  • Having a chronic dermatosis liable to modify the cutaneous reactivity on the tested area (except for specific studies on a determined dermatosis)
  • Being known thyroid case
  • Being epileptic.
  • Following a chronic medicinal treatment comprising any of the following products: aspirin-based products, anti-inflammatories, anti-histamines, corticotherapy, taken by general or local routes or corticosteroid by any route (the only medication permitted is paracetamol)
  • Known case of hypersensitivity.

Outcomes

Primary Outcomes

skin moisturization and skin barrier function

Time Frame: T0, 30 Minutes, 24 hours, 48 hours & 72 Hours after product application

Secondary Outcomes

No secondary outcomes reported

Investigators

Sponsor Class
Pharmaceutical industry-Indian
Responsible Party
Principal Investigator
Principal Investigator

Dr Pooja Yadav

MASCOT-SPINCONTROL India Pvt. Ltd.

Study Sites (1)

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