Towards molecular characterization of sporadic epithelial ovarian carcinoma
Completed
- Conditions
- ovarian cancer10038594
- Registration Number
- NL-OMON38084
- Lead Sponsor
- Academisch Medisch Centrum
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- Not specified
- Target Recruitment
- 600
Inclusion Criteria
Women with an ovarian carcinoma, all histological subtypes and all stages and grades will be included. Approximately 300 new patients suspected of ovarian cancer are expected each year within the CGOA (AMC, AvL/NKI, VUmc), of whom 100 are expected to be diagnosed with a benign ovarian tumour, and 200 with a malignant ovarian tumour.
Exclusion Criteria
Women with an expected benign ovarian tumour.
Study & Design
- Study Type
- Observational non invasive
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method <p>By combining techniques and apllying them to the same large series of patients,<br /><br>we aim to fully describe the characteristics of ovarian carcinomas that<br /><br>determine whether or not a patient reponds well to her treatment. We hope to be<br /><br>able to discriminate subclasses of ovarian cancer that offer leads for novel<br /><br>therapeutic approaches. By using the infrastructure of the cooperation that has<br /><br>been set up between the various medical centers we will set up new pospective<br /><br>clinical trials for the treatment of ovarian cancer based on the protein and<br /><br>genetic information generated by our studies.</p><br>
- Secondary Outcome Measures
Name Time Method <p>Not applicable. </p><br>