NCT02877745Unknown不适用
ImpaCt of Sleep-disOrdered breathiNg on Atrial Fibrillation and Perioperative complicationS In Patients unDERgoing Coronary Artery Bypass graFting Surgery
Michael Arzt1 个研究点 分布在 1 个国家目标入组 1,200 人开始时间: 2016年7月最近更新:
适应症
试验速览
- 阶段
- 不适用
- 发起方
- 入组人数
- 1,200
- 试验地点
- 1
- 主要终点
- Major Adverse Cardiac and Cerebrovascular Events (MACCE)
研究概览
简要总结
In patients undergoing elective coronary artery bypass grafting (CABG) surgery, coronary artery disease, sleep-disordered breathing (SDB), atrial fibrillation (AF) perioperative atrial fibrillation and complications will be assessed. The primary objective is to determine, whether SDB patients have a higher rate of Major Adverse Cardiac and Cerebrovascular Events (MACCE) within 30 days after surgery compared to those without SDB.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 85 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Patients undergoing elective CABG surgery at the Department of Cardiac and Thoracic Surgery, University Hospital Regensburg.
- •Written informed consent
排除标准
- •Preoperative use of inotropes or intra aortic balloon pump
- •Severe obstructive pulmonary disease
- •Patients on oxygen therapy, nocturnal positive airway pressure support or mechanical ventilation
结局指标
主要结局
Major Adverse Cardiac and Cerebrovascular Events (MACCE)
时间窗: 30 days
periprocedural and late myocardial infarction (MI), non-fatal stroke and transitory ischemic attack (TIA) as well as all-cause mortality
次要结局
- postoperative atrial fibrillation (POAF)(30 days after CABG surgery)
- Stroke(within 1 year after CABG surgery)
- MACCE(within 1 and 2 years after CABG surgery)
- Major pulmonary complications(within 30 days as well as 1 and 2 years)
研究者
Michael Arzt
Coordinating Investigator
University Hospital Regensburg
研究点 (1)
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