Recovery of movement and sensation after stroke

Not Applicable

Completed

• Conditions: Stroke; Stroke - Haemorrhagic; Neurological - Other neurological disorders; Stroke - Ischaemic

• Registration Number: ACTRN12617000559314
• Lead Sponsor: The University of Auckland

Brief Summary

ot yet available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2017-04-21
• Study Completion: 2020-08-31
• Last Update Posted: 21 July 2021

Recruitment & Eligibility

• Status: Completed
• Sex: All
• Target Recruitment: 25

Inclusion Criteria

Aged 18 years or more
Diagnosis of monohemispheric cerebral ischaemic or haemorrhagic stroke within the previous week
Weakness and/or sensory loss on one side of the body as a result of stroke

Exclusion Criteria

Cerebellar stroke
Contraindications to non-invasive brain stimulation or MRI
Pre-existing neurological or musculoskeletal condition affecting movement or sensation
Cognitive and/or communication impairment precluding informed consent or compliance with testing procedures.
Life expectancy less than 12 months
Resides out of the Auckland region, precluding follow-up assessments

Study & Design

• Study Type: Observational
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Proportion of initial upper limb motor impairment recovered at plateau, assessed with the upper extremity Fugl-Meyer scale.[Assessed weekly for the first 4 weeks post-stroke, and then fortnightly up to six months post-stroke, in order to determine plateau.];Proportion of initial upper limb cutaneous sensory impairment recovered at plateau, assessed with monofilaments applied to the base of the thumb.[Assessed weekly for the first 4 weeks post-stroke, and then fortnightly up to six months post-stroke, in order to determine plateau.];Proportion of initial lower limb motor impairment recovered at plateau, assessed with the lower extremity Fugl-Meyer scale.[Assessed weekly for the first 4 weeks post-stroke, and then fortnightly up to six months post-stroke, in order to determine plateau.]

Secondary Outcome Measures

Name	Time	Method
The proportional recovery from upper limb cutaneous sensory impairment, measured with monofilaments, will be compared between patients who have detectable N20 somatosensory evoked potentials in the ipsilesional hemisphere and those who do not.[Six months post-stroke];The time post-stroke at which plateau is reached in the recovery from upper limb cutaneous sensory impairment (measured with monofilaments) and the recovery from upper limb motor impairment (measured with the upper extremity Fugl-Meyer scale) will be compared.[Six months post-stroke.]