IRCT20180417039347N1
Recruiting
Phase 3
Prophylactic effect of N-acetyl-cysteine plus Atorvastatin versus N-acetyl-cysteine and Atorvastatin alone for the prevention of contrast induced nephropathy in patients undergoing elective angiography with or without percutaneous coronary intervention: a single center prospective randomized controlled trial
Zahedan University of Medical Sciences0 sites250 target enrollmentTBD
Overview
- Phase
- Phase 3
- Intervention
- Not specified
- Conditions
- Contrast induced nephropathy.
- Sponsor
- Zahedan University of Medical Sciences
- Enrollment
- 250
- Status
- Recruiting
- Last Updated
- 5 years ago
Overview
Brief Summary
No summary available.
Investigators
Eligibility Criteria
Inclusion Criteria
- •Eligible patients include individuals older than 21 years old
- •abnormal renal function (Creatinine clearance between 15 and 60 mL/min or serum creatinine (SCr) \=1\.1 mg/dL)
- •Undergoing elective cardiac catheterization with or without PCI
Exclusion Criteria
- •Patients with end\-stage renal failure (glomerular filtration rate (GFR) \= 15 mL/min),
- •history of previous dialysis
- •pulmonary edema
- •emergency cardiac catheterization (patients with ST\-segment elevation myocardial infarction undergoing primary PCI ),
- •exposure to contrast within previous two days ago before procedure
- •allergies to contrast media,
- •contraindication to statins
- •liver disease
Outcomes
Primary Outcomes
Not specified
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