Effect of Repetitive Transcranial Magnetic Stimulation on Motor Functions in Multiple Sclerosis Patients
- Conditions
- Nervous System Diseases
- Registration Number
- PACTR201907475143673
- Lead Sponsor
- Cairo university.
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete
- Sex
- All
- Target Recruitment
- 30
1)Definite diagnosis of relapsing-remitting multiple sclerosis, fulfilled the Revised McDonald's criteria for diagnosis of multiple sclerosis 2010 (Polman et al., 2011).
2)A score of 2.0 to 4.0 on the Expanded Disability Status Scale (EDSS).
3)Age ranges from 20 – 40 years old.
4)All the patients are in the remission period.
5) Last attack occurs at least since two months.
6)All the Patients are ambulant.
7)All patients are receiving the same medical treatment.
8) Patients are medically stable.
9)Ability to understand and follow instructions.
10)The Patients are free from any secondary complications such as contractures or deformities.
11)The patients recruited with informed consent.
1)Any other neurological deficits or orthopedics abnormalities preventing participation in the study.
2)Patients who have any other inflammatory or infectious diseases, e.g. arthritis.
3)Pregnant female patients.
4)Cardiovascular and Pulmonary diseases.
5)Patients with active or uncontrolled pathologies (i.e. cancer).
6)Patients in acute relapse stage.
7)Patients with cognitive deficits.
8)Patients with any psychiatric disease.
9)Patients with magnetic devices or any other implanted device.
10)History of seizure.
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Isokinetic dynamometer which measures the peak toque, peak torque/body weight (PK/BW), time to peak torque, total work and average power.
- Secondary Outcome Measures
Name Time Method Five repititions sit to stand test which measures the functional lower extremity strength.