High-resolution CE-MRA of Children's Hip Joint

Completed

• Conditions: Hip; Vessels; Anomaly; Magnetic Resonance; Three-dimensional Water-selective Cartilage (3D-WATSc)
• Interventions: Other: Magnetic resonance examination

• Registration Number: NCT05754905
• Lead Sponsor: Children's Hospital of Chongqing Medical University

Brief Summary

The goal of this observational study is to learn about the feasibility of enhanced three-dimensional water-selective cartilage (3D-WATSc) sequence in displaying the vessels of children's hip by magnetic resonance. The main questions it aims to answer are:

* Could the images of enhanced 3D-WATSc sequence show the healthy side hip joint vessels in children?

* Could the images of enhanced 3D-WATSc sequence show the vascular disease of the suffering side hip joint in children?

Participants with unilateral hip disease will undergo the magnetic resonance examination including enhanced 3D-WATSc sequence. The pelvic plain film and magnetic resonance images will be collected and analysed.

Researchers will compare the images of of the normal side with the images of the abnormal side to see if the enhanced 3D-WATSc sequence images could show the vascular disease of the suffering side hip joint in children?

Detailed Description

Not available

Study Timeline

• Study Start: 2021-01-01
• Primary Completion: 2022-12-30
• Study Completion: 2023-01-31
• Status Verified: 2023-02
• Study First Submitted: 2023-02-23
• Study First Submitted QC: 2023-03-03
• Last Update Submitted: 2023-03-03
• Study First Posted: 2023-03-06
• Last Update Posted: 2023-03-06

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 48

Inclusion Criteria

• Children aged 6 months-14 years who are diagnosed as hip disease after screening by pediatric orthopedic surgeon in Children's Hospital of Chongqing Medical University during the study period. The hip disease contain developmental dysplasia of the hip, Perthes disease, infection of the hip, inflammation of the hip, fracture of the hip, and Meyer's dysplasia.

Exclusion Criteria

• patients with bilateral hip joint disease; patients with claustrophobia;Patients with metal implants (such as pacemaker implantation)

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Arm && Interventions

Group	Intervention	Description
Normal hip joint	Magnetic resonance examination	The normal side of patients with hip joint disease
Abnormal hip joint	Magnetic resonance examination	The abnormal side of patients with hip joint disease

Primary Outcome Measures

Name	Time	Method
The branches of the MCFA and/or LCFA around the bilateral femoral neck	1 day (Magnetic resonance examination end time)	Morphology of MCFA and/or LCFA branches around the bilateral femoral neck
The medial circumflex femoral artery (MCFA) and lateral circumflex femoral artery (LCFA) of the bilateral hip joint	1 day (Magnetic resonance examination end time)	Morphology of the MCFA and LCFA of the bilateral hip joint
The vessels of secondary ossification center and/or cartilaginous vascular canal in bilateral femoral head	1 day (Magnetic resonance examination end time)	Morphology of the vessels and cartilaginous vascular canal in bilateral femoral head

Trial Locations

Locations (1)

Children's Hospital of Chongqing Medical University; 🇨🇳 Chongqing, Chongqing, China