Thrombelastogram in Patients Receiving Antiplatelet Medication Undergoing Cardiac Surgery
- Conditions
- Bleeding
- Registration Number
- NCT00778492
- Lead Sponsor
- Sheba Medical Center
- Brief Summary
Study Objective is to correlate the results of preoperative platelet mapping derived from modified TEG with clinically significant postoperative bleeding and consumption of blood products.
- Detailed Description
Study Design:
Prospective observational study with blinded assessment of study endpoint variables. Collection of information concerning study endpoints will be performed by the investigator blinded to the results of preoperative testing of platelet function. The information will be collected from 60 patients undergoing cardiac surgery in the Department of Cardiac Surgery of Sheba Medical Center.
Study endpoints
1. Primary endpoint- resternotomy for bleeding after the surgery.
2. Secondary endpoints- chest tube output during first 24 hours after the surgery; consumption of blood products during first 3 postoperative days.
Recruitment & Eligibility
- Status
- UNKNOWN
- Sex
- All
- Target Recruitment
- 60
- Patients undergoing cardiac surgery with the history of aspirin and/or ADP receptor antagonist for at least 7 days prior the surgery
- Emergent surgery
- Heart transplant surgery
- Implantation of ventricular assist devices
- Enrollment into conflicting study
Study & Design
- Study Type
- OBSERVATIONAL
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Re-sternotomy d/t Bleeding Hospitalization Period
- Secondary Outcome Measures
Name Time Method Chest tube output during first 24 hours after the surgery 24 hours
Trial Locations
- Locations (1)
Sheba Medical Center
🇮🇱Tel Hashomer, Israel