Assessment of Depression Levels in Elderly Patients With an Orthopedic Fracture Compared to Patients After a Stroke.
Not Applicable
Active, not recruiting
- Conditions
- DepressionOld AgeDebilityStrokeFractures, Bone
- Registration Number
- NCT06570356
- Lead Sponsor
- Shmuel Harofeh Hospital, Geriatric Medical Center
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Active, not recruiting
- Sex
- All
- Target Recruitment
- 400
Inclusion Criteria
Inclusion Criteria:<br><br> - Age > 65 and hospitalization after stroke or fracture<br><br>Exclusion Criteria:<br><br> - Prior diagnosis of depression/current antidepressant treatment before<br> hospitalization/ significant cognitive decline as indicated by a Mini-Mental State<br> Examination (MMSE) score below 20/lacking the capacity to provide informed consent.
Exclusion Criteria
Not provided
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Depression symptoms prevalence assessed by the Geriatric Depression Scale-15
- Secondary Outcome Measures
Name Time Method
Related Research Topics
Explore scientific publications, clinical data analysis, treatment approaches, and expert-compiled information related to the mechanisms and outcomes of this trial. Click any topic for comprehensive research insights.
What molecular mechanisms underlie post-fracture depression compared to post-stroke depression in elderly patients?
How do standard-of-care antidepressants like SSRIs affect outcomes in elderly patients with orthopedic fractures versus stroke-induced depression?
Which biomarkers (e.g., inflammatory cytokines, neurotrophic factors) correlate with depression severity in hip fracture vs. ischemic stroke patients?
What adverse events are reported in elderly populations receiving pharmacological vs. non-pharmacological depression treatments after fractures or stroke?
Are there synergistic effects of combining antidepressants with bone regeneration therapies for elderly patients with traumatic fractures and comorbid depression?