Efficacy of Serratus Anterior Plane Block Mastectomy

Not Applicable

Completed

• Conditions: Postoperative Complications; Postoperative Pain
• Interventions: Procedure: serratus anterior plan block

• Registration Number: NCT03944759
• Lead Sponsor: doaa rashwan

Brief Summary

Breast cancer is the main common cancer among females. . Inadequate control of pain may later develop into chronic pain syndrome (paraesthesias, phantom breast pain, and intercostobrachial neuralgia) in 25-40% of the patients .

Detailed Description

The aim of this study is to compare the efficacy of ultrasound-guided serratus anterior plane block with bupivacaine/ magnesium versus bupivacaine/ nalbuphine in breast cancer surgery.

Patients and methods nclusion criteria:

-ASA I and II female patients, age 25-60 undergoing breast cancer surgery

Exclusion criteria:

* Patient refusal

* Contraindications for regional blocks (eg. Infection at the injection site, coagulopathy)

* Allergy to the drugs used in the study

* Chronic pain therapy,

* BMI more than 30 kg/m2

Study Timeline

• Study First Submitted: 2019-05-06
• Study Start: 2019-05-07
• Study First Submitted QC: 2019-05-08
• Study First Posted: 2019-05-10
• Primary Completion: 2019-12-01
• Study Completion: 2019-12-01
• Status Verified: 2020-02
• Last Update Submitted: 2020-02-11
• Last Update Posted: 2020-02-12

Recruitment & Eligibility

• Status: COMPLETED
• Sex: Female
• Target Recruitment: 40

Inclusion Criteria

• ASA I and II female patients, age 25-60 undergoing breast cancer surgery

Exclusion Criteria

• -Patient refusal
• Contraindications for regional blocks (eg. Infection at the injection site, coagulopathy)
• Allergy to the drugs used in the study
• Chronic pain therapy,
• BMI more than 30 kg/m2

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
GBM:( bupivacaine/magnesium sulphate)	serratus anterior plan block	serratus plane block will performed in the supine position under strict aseptic conditions before induction of anesthesia. GBM:( bupivacaine/magnesium sulphate): will receive bupivacaine 30 ml 0.25 and 500 mg magnesium sulphate
GBN: ( bupivacaine/nalpuphin)	serratus anterior plan block	serratus plane block will performed in the supine position under strict aseptic conditions before induction of anesthesia.. ( bupivacaine/nalpuphin):received bupivacaine 30 ml 0.25 % and nalpuphine 0.2mg/kg.

Primary Outcome Measures

Name	Time	Method
time to first analgesic requirements in minutes	change from base line for 24 hours	time to first analgesic requirements in minutes by the patient

Trial Locations

Locations (1)

Faculty Of Medicine, Beni-Suef University; 🇪🇬 Banī Suwayf, Egypt