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Herbo-Mineral Solution having potential antimicrobial properties in cleansing of infected wounds.

Phase 2/3
Not yet recruiting
Conditions
Other specified local infections of the skin and subcutaneous tissue. Ayurveda Condition: DUSHTAVRANAH,
Registration Number
CTRI/2023/11/060378
Lead Sponsor
DepartmParul Institute Of Ayurveda Parul University Waghodia Road Vadodara Gujarat India
Brief Summary

As per Ayurveda wound is explained in the chapter of Vrana. Which is defined as “Vrana gatra vichurnane vranayati iti vranaha†meaning the destruction / break / rupture / discontinuity of the body tissues is called as  Vrana. So, “Vrana Gatra Vichurnaneâ€i means phenomenon complex causing destruction or Rupture or discontinuation of tissues in a particular part of the body which is termed as Vrana, whereas Vranayati means discoloration.

Hence, the definition of Vrana implies the damage of a part of the body leading to disfigurement and discoloration. In Sushruta Samhita, Acharya has clarified that as the Vranavastu (scars) of a Vrana (wound) never disappears after complete healing and its imprint persists lifelong, that lesion is called as Vrana.

Aacharya Sushruta has described 2 types of vrana e.g. sharira and aagantuja. Dustha vrana and its detail signs e.g. atisanvruta, ativivruta, ati kathina, atimrudu etc are described in

chapter of  Vranasrava vignaniya.. Aacharya Sushruta  also mentioned other details of vrana e.g. vranasrava, vranavarna, vranasthana etc. and its management which is of prime importance in any surgical practice or procedure.

As dusta vrana (inected wounds) are a frequently encountered problem in present era commonly as a complication of trauma and pathological insult. Dustha vrana are long lasting and non-healing ulcer, where removing debris to reach healthy tissues is a prime focus. So we can say that  in dusta vrana there is localization of dosha that prevents vrana to heal and disturbs natural process of healing. By seeing its aspect of management we should treat this type of vrana  as early as possible so that we can prevent delayed  healing causing factors.

Acharya sushruta  was aware of importance of vrana management, so he mentioned 60 upakramas  for vrana  management which include local as well as the systematic use of different drugs and treatment modalities under dedicated chapters.

Acharya Sushruta “The Father of Indian Surgery†has explained  Vrana in detail in his classical text “Sushruta Samhitaâ€.The term Wound is a discontinuity or break in the surface epithelium. A wound is simple when only skin is involved. It is complex when it involves underlying nerves, vessels and tendons.



Worldwide prevalence of wound ranges from 0.18% to 0.32% of world population and incidence is 0.78% of population. Prevalence of wounds in Indian population is 4.48/1000.There are many different types of wounds even though all the wounds follow the same healing process roughly.

As the science have advanced, newer therapies are tried out to boast up cleansing and the recovery process, but the oldest remedies still lead the race. Aacharya sushruta has explained Vrana in detail in his classical text and many Vrana Shodhana dravyas for the same and that still holds its place today.

Detailed Description

Not available

Recruitment & Eligibility

Status
Not Yet Recruiting
Sex
All
Target Recruitment
12
Inclusion Criteria

Patients of Dushta Vrana will be selected irrespective of gender, religion, occupation and socio-economic status 2.Patients between 20-60 years of age 3.Patients suffering from Dushta Vrana as per classic.

Exclusion Criteria
  • Malignancy 2.
  • Syphilis 3.
  • Tuberculosis 4.
  • Uncontrolled Diabetes mellitus 10.
  • Ostiomylitis 11.

Study & Design

Study Type
Interventional
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
Early Wound Cleansing and HealingEarly Wound Cleansing and Healing within 1 month
Secondary Outcome Measures
NameTimeMethod
early wound cleansing with assessment on 7th 14th 21st and on 28th day7th 14th 21st and on 28th day

Trial Locations

Locations (1)

Parul Ayurveda Hospital

🇮🇳

Vadodara, GUJARAT, India

Parul Ayurveda Hospital
🇮🇳Vadodara, GUJARAT, India
Dr Megha Jadhav
Principal investigator
9767012312
13meghavj@gmail.com

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