Skip to main content
Clinical Trials/TCTR20190719001
TCTR20190719001
Enrolling By Invitation
Phase 3

Effectiveness of one-week versus two-week combination amphotericin B and flucytosine for induction therapy of HIV-associated cryptococcal meningitis

Faculty of Medicine Siriraj Hospital0 sites105 target enrollmentJuly 19, 2019

Overview

Phase
Phase 3
Intervention
Not specified
Conditions
Age more than 18 yearsHIV infectionDiagnosis of cryptococcal meningoencephalitis
Sponsor
Faculty of Medicine Siriraj Hospital
Enrollment
105
Status
Enrolling By Invitation
Last Updated
last year

Overview

Brief Summary

No summary available.

Registry
who.int
Start Date
July 19, 2019
End Date
June 30, 2021
Last Updated
last year
Study Type
Interventional
Sex
All

Investigators

Eligibility Criteria

Inclusion Criteria

  • 1\. HIV\-infected patients, 18 years of age or older,
  • 2\. Admitted at Siriraj Hospital and another 11 hospitals
  • 3\. Definite diagnosis of cryptococcal meningitis

Exclusion Criteria

  • 1\. Allergic to amphotericin B or flucytosine
  • 2\. Receive amphotericin B or flucytosine more than 72 hours
  • 3\. Women who were pregnant or during breast feeding
  • 4\. Other fungal infection which treatment by amphotericin B

Outcomes

Primary Outcomes

Not specified

Similar Trials