Randomized, controlled study comparing two mouthwashes with regard to taste assessment and reduction of oral mucosa in oncological patients -Octenidol® vs. Glandomed®

Not Applicable

• Conditions: mucositis; K12.3; Oral mucositis (ulcerative)

• Registration Number: DRKS00011318
• Lead Sponsor: Fa. Schülke GmbH

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Completion: 2010-11-30
• Study Start: 2016-11-17
• Last Update Posted: 19 August 2024

Recruitment & Eligibility

• Status: Complete
• Sex: All
• Target Recruitment: 93

Inclusion Criteria

• Participants> 18 years
• Signed declaration of consent to participate or
Written declaration of consent by the supervisor
• German speaking
• oncological patients (KMT autologous or allogeneic)

Exclusion Criteria

• Mental disorders
• Existing mucositis before radiation therapy / chemotherapy
• Current therapy with chemotherapy or irradiation
• Incompatibility with CHX or octenidine
• Temperatures> 38 degrees Celsius before irradiation / chemotherapy
• Dental defect or loose teeth
• Infection of the upper respiratory tract

Study & Design

• Study Type: interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
State of mucositis by standardc scores.OMAS-Skala (Oral mucositis assessment scoale) and WHO-Skala zur Mucositis)The parameters are measured at three times in day 0, day 3, day 5 and day 14 in the morning)

Secondary Outcome Measures

Name	Time	Method
Pain (visuel analogue scale), difficulties in swallowing, temperature, microbiological tests of saliva (bacterial material)The parameters are measured at three times, in day 0, day 3 day 5 and day 14 in the morning)