Motion Sickness on Astrolabe's Vessel

Completed

• Conditions: Sea Sickness

• Registration Number: NCT02911402
• Lead Sponsor: University Hospital, Caen

Brief Summary

Sea sickness syndrome is present for 80% of persons on board when the boat rotation missions Astrolabe, sometimes there is a risk of very significant dehydration. A special unit specialized in the fundamental study of the vestibular system (inner ear), sensory organ at the base of visual-vestibular conflict inducing this syndrome, also provides medical support for parabolic flights (flight reproducing weightlessness) where this syndrome is strongly present. The goal of the study is to assess the frequency of occurrence of this sea sickness syndrome on the Astrolabe, to understand the triggers (type of boat movements, personality traits, anxiety / stress) without changing habits on board for those on board taking a antinaupathique treatment given by the ship's doctor. This study will be done in collaboration between INSERM U 1075 (France) and the Laboratory of military research VIPER specialized in extreme environments (Belgium). The ultimate goal will be to provide the best recommendations and the best treatment regimen to alleviate as best as possible the symptoms of people on board of the Astrolabe so scientists on board can perform their work.

Detailed Description

Background: The objectives were to assess the prevalence, severity, medication taken and to look for predictive factors, in order to better identify characteristics of passengers at risk of motion sickness during transport scientists travelling from Hobart in Tasmania to the French polar stations in Antarctica.

Methods: Two hundred and thirty-nine passengers were surveyed over 4 years with 4 round trips per year using Motion Sickness Susceptibility Questionnaire (MSSQ), Simulator Sickness Questionnaire (SSQ), state-trait anxiety test (STAI-Trait and STAI-State), and general parameters (age, gender, number of trips, jet-lag, direction of the trip), medication, calculation of the distance of each passenger's cabin to the Centre of Gravity (CoG.).

Study Timeline

• Study Start: 2014-10
• Study First Submitted: 2016-09-20
• Study First Submitted QC: 2016-09-20
• Study First Posted: 2016-09-22
• Primary Completion: 2017-12
• Study Completion: 2018-12
• Status Verified: 2022-01
• Last Update Submitted: 2022-01-31
• Last Update Posted: 2022-02-15

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 147

Inclusion Criteria

• participant aged of 18 or older but younger than 70 who received their medical ability to travel to Terre Adélie or making a research cruise aboard the Astrolabe
• particpant signing the informed consent.

Exclusion Criteria

• none

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Motion Sickness susceptibilty questionnaire (fMSSQ)	day 1 to day 10	Sensitivity of motion sickness
STAY-YA questionnaire	day 1 to day 10	anxiety
Fatigue questionnaire	day 1 to day 10	Tiredness
Dietary intake survey	day 1 to day 10	food intake
Vis-Morgen Questonnaire about sleeping	day 1 to day 10	Subjective sleep scoring
STAY-YB questionnaire	day 1 to day 10	anxiety

Secondary Outcome Measures

Name	Time	Method
personnality questionnaire (OCEAN)	baseline and every day up to 10 days	Personnality
anxiety questionnaire (STAY).	baseline and every day up to 10 days	anxiety
treatment taken (international denomination and dose)	baseline and every day up to 6 days	treatment taken by subject for motion sickness
data from individual actigraphs worn by the participants	baseline and every day up to 10 days	this will allow to quantify particpant's movements related to the ship movement
type of movement from the ship using use the data from the Dynamic Positioning System on board	baseline and every day up to 10 days	boat motion

Trial Locations

Locations (1)

Caen University Hospital; 🇫🇷 Caen, France