Precision Medicine in Ischemic Stroke and Atrial Fibrillation
Trial Snapshot
- Phase
- Not Applicable
- Status
- Completed
- Enrollment
- 805
- Locations
- 2
- Primary Endpoint
- Incidence of cardiac rhythm monitoring
Study Overview
Brief Summary
The overall goal of this study is to minimize morbidity due to Atrial Fibrillation (AF). The specific objective is to develop and implement a rational and personalized approach to AF risk estimation that can inform management decisions with ischemic stroke. The investigators propose to develop a clinical AF risk estimation tool in the electronic health record and to test the effectiveness of implementing a clinical AF risk estimation tool into care for use by stroke neurologists during the care of acute ischemic stroke patients at Massachusetts General Hospital. The investigators will evaluate cardiac monitoring utilization calibrated to AF risk by stroke neurologists using a custom electronic health record (EHR) notification module.
The investigators hypothesize that cardiac rhythm monitoring utilization will be positively correlated with the predicted risk of AF.
Study Design
- Study Type
- Interventional
- Allocation
- Na
- Intervention Model
- Single Group
- Primary Purpose
- Screening
- Masking
- None
Eligibility Criteria
- Ages
- 18 Years to — (Adult, Older Adult)
- Sex
- All
- Accepts Healthy Volunteers
- No
Inclusion Criteria
- •Patients aged 18 years or older
- •Presenting with a primary diagnosis of ischemic stroke or transient ischemic attack admitted to Massachusetts General Hospital inpatient stroke service
Exclusion Criteria
- •Patients not meeting above inclusion criteria
Outcomes
Primary Outcomes
Incidence of cardiac rhythm monitoring
Time Frame: 6-months
Incidence of any cardiac rhythm monitoring in the 6-month follow-up period following discharge for an acute ischemic stroke. Cardiac rhythm monitoring will be ascertained based on electronic health record documentation.
Secondary Outcomes
- Proportion of patients with a new atrial fibrillation diagnosis(12-months)
- Proportion of patients with oral anticoagulation prescription(12-months)
- Proportion of patients with implantable loop recorder orders(12-months)
- Proportion of patients with cardiac monitor ordered by neurologist(1-month)
- Proportion of patients with recurrent stroke(12-months)
- Proportion of patients with transesophageal echocardiogram utilization(3-months)
- Proportion of patients with ambulatory wearable cardiac rhythm monitoring orders(12-months)
- Proportion of patients deceased(12-months)
Investigators
Christopher D. Anderson, MD, MMSc
Division Chief
Brigham and Women's Hospital