Precision Medicine in Ischemic Stroke and Atrial Fibrillation
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 805
- 试验地点
- 2
- 主要终点
- Incidence of cardiac rhythm monitoring
研究概览
简要总结
The overall goal of this study is to minimize morbidity due to Atrial Fibrillation (AF). The specific objective is to develop and implement a rational and personalized approach to AF risk estimation that can inform management decisions with ischemic stroke. The investigators propose to develop a clinical AF risk estimation tool in the electronic health record and to test the effectiveness of implementing a clinical AF risk estimation tool into care for use by stroke neurologists during the care of acute ischemic stroke patients at Massachusetts General Hospital. The investigators will evaluate cardiac monitoring utilization calibrated to AF risk by stroke neurologists using a custom electronic health record (EHR) notification module.
The investigators hypothesize that cardiac rhythm monitoring utilization will be positively correlated with the predicted risk of AF.
研究设计
- 研究类型
- Interventional
- 分配方式
- Na
- 干预模型
- Single Group
- 主要目的
- Screening
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Patients aged 18 years or older
- •Presenting with a primary diagnosis of ischemic stroke or transient ischemic attack admitted to Massachusetts General Hospital inpatient stroke service
排除标准
- •Patients not meeting above inclusion criteria
结局指标
主要结局
Incidence of cardiac rhythm monitoring
时间窗: 6-months
Incidence of any cardiac rhythm monitoring in the 6-month follow-up period following discharge for an acute ischemic stroke. Cardiac rhythm monitoring will be ascertained based on electronic health record documentation.
次要结局
- Proportion of patients with a new atrial fibrillation diagnosis(12-months)
- Proportion of patients with oral anticoagulation prescription(12-months)
- Proportion of patients with implantable loop recorder orders(12-months)
- Proportion of patients with cardiac monitor ordered by neurologist(1-month)
- Proportion of patients with recurrent stroke(12-months)
- Proportion of patients with transesophageal echocardiogram utilization(3-months)
- Proportion of patients with ambulatory wearable cardiac rhythm monitoring orders(12-months)
- Proportion of patients deceased(12-months)
研究者
Christopher D. Anderson, MD, MMSc
Division Chief
Brigham and Women's Hospital