SURVIVAL PLUSS: Increasing Capacity for Mama-baby Survival in Post-conflict Uganda and South Sudan

Not Applicable

Completed

• Conditions: Neonatal Death; Preterm Birth; Low Birthweight; Neonatal Hypoglycemia

• Registration Number: NCT02605369
• Lead Sponsor: Makerere University

Brief Summary

Universal coverage of good quality facility based care globally could prevent nearly 113,000 maternal deaths, 531,000 stillbirths and 1.3 million neonatal deaths annually by 2020. Yet, only 57% of pregnant Ugandan women choose to deliver at health facilities. This unacceptably low coverage of facility based births could explain, in part, the high maternal and perinatal mortality estimates in Uganda. While multiple studies have examined factors associated with this low utilization of health services around the time of birth, there is inadequate implementation research exploring the best systematic methods that could promote uptake and scale up of facility based births. This study will therefore examine the effect of an intervention package (peer counselling by pregnancy buddies on facility based births, mobile phone messaging promoting facility based births and provision of mama-kits) on the frequency of facility based births and perinatal mortality. The study, a cluster randomized community based intervention trial in post-conflict Northern Uganda, will provide data crucial in framing national policy regarding measures to promote the use of health facilities.

Detailed Description

Not available

Study Timeline

• Study First Submitted: 2015-11-12
• Study First Submitted QC: 2015-11-12
• Study First Posted: 2015-11-16
• Study Start: 2018-01-03
• Primary Completion: 2019-02-28
• Study Completion: 2019-02-28
• Status Verified: 2023-10
• Last Update Submitted: 2023-10-07
• Last Update Posted: 2023-10-10

Recruitment & Eligibility

• Status: COMPLETED
• Sex: Female
• Target Recruitment: 1877

Inclusion Criteria

• Pregnant women at 28 or more weeks of gestation
• Residence in the selected clusters
• Pregnant women under 18 years of age will be included since they are considered as emancipated minors in Uganda

Exclusion Criteria

• Intention to move from the study area within one year
• Psychiatric ailments that may inhibit the informed consent process

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Primary Outcome Measures

Name	Time	Method
Facility based birth	Day 1	Delivery at a health facility

Secondary Outcome Measures

Name	Time	Method
Neonatal death	Day 28	Death within the first month of life
Timely initiation of breastfeeding	Up-to one hour after birth	Initiation of breastfeeding with the first hour after birth
Severe illness	Day 28	Severe illness within the first month of life
The percent of newborns attended by a health care pro-vider during the first 48 hours following birth	Up-to 48 hours after birth	Proportion of babies seen by a health care work in the first 48 hours after birth
The percent of newborns attended by a health care pro-vider during the first 7 days following birth	1 week	Proportion of babies seen by a health care work in the first one week after birth

Trial Locations

Locations (1)

Lira District; 🇺🇬 Lira, Uganda