跳至主要内容
临床试验/NCT02399696
NCT02399696已完成不适用

Primary Care-Based Mindfulness Intervention for Veterans With PTSD

Syracuse VA Medical Center0 个研究点目标入组 62 人开始时间: 2013年3月1日最近更新:
适应症

试验速览

阶段
不适用
状态
已完成
发起方
入组人数
62
主要终点
PTSD symptoms as measured by the PTSD Checklist

研究概览

简要总结

Primary care patients typically do not receive adequate PTSD treatment because of their reluctance to engage in empirically-supported treatments offered in specialty care settings. Effective treatments for PTSD are also typically not provided in primary care. Brief skill-based treatments offered in primary care may alleviate symptoms and prepare patients to engage in additional treatment. VA primary care patients with PTSD (N=62) were recruited for a randomized clinical trial comparing a Primary Care-Brief Mindfulness Program (PC-bMP) to primary care-treatment as usual (PC-TAU). PC-bMP is a 4-week group program adapted from the 8-week Mindfulness Based Stress Reduction (MBSR) curriculum. Veterans in the PC-bMP condition demonstrated significantly greater decreases in PTSD and depressive symptoms from pre-treatment to post-treatment compared to PC-TAU. These gains were maintained at 8 and 12 week follow-up. PC-bMP participants experienced clinically significant decreases in PTSD, averaging a 15-point drop on the Clinician-Administered PTSD Scale. Exploratory analyses revealed that the describing, non-judging, and acting with awareness facets of mindfulness may account for decreases in PTSD. Our data support preliminary efficacy of a brief mindfulness-based intervention for Veterans with PTSD in primary care. Further research is needed to investigate how PC-bMP may facilitate engagement into full length empirically-supported treatment for PTSD.

研究设计

研究类型
Interventional
分配方式
Randomized
干预模型
Parallel
主要目的
Treatment
盲法
Single (Outcomes Assessor)

入排标准

年龄范围
18 Years 至 —(Adult, Older Adult)
性别
All
接受健康志愿者

入选标准

  • sub-threshold or diagnostic level PTSD related to military service as determined by the Clinician Administered PTSD Scale

排除标准

  • gross cognitive impairment, 2) moderate to severe traumatic brain injury, 3) suicide attempt or intent to commit suicide in the last two months, and 4) receipt of mental healthcare (psychotherapy or medication) outside VA primary in the last two months.

结局指标

主要结局

PTSD symptoms as measured by the PTSD Checklist

时间窗: 8 weeks

次要结局

  • Depression symptoms as measured by the Patient Health Questionaire-9(8 weeks)

研究者

发起方
Syracuse VA Medical Center
申办方类型
Fed
责任方
Principal Investigator
主要研究者

Kyle Possemato

Clinical Research Psychologists

Syracuse VA Medical Center

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