CTRI/2025/08/092167尚未招募2/3 期
Clinical efficacy of Aspirin and Erythropoietin loaded injectable hydrogels as a Local Drug Delivery system in the treatment of intrabony defects a Randomized control trial
DR ASMA ANJUM I1 个研究点 分布在 1 个国家目标入组 40 人开始时间: 2025年8月17日最近更新:
试验速览
- 阶段
- 2/3 期
- 状态
- 尚未招募
- 发起方
- 入组人数
- 40
- 试验地点
- 1
- 主要终点
- radiographic parameter of vertical defect on CBCT Biochemical parameter of assessing the BMP2 levels
研究概览
简要总结
To evaluate the effect of scaling and root planing (SRP) alone in intra bony defects
To evaluate the effect of scaling and root planing with injectable hydrogels in intra bony defects
To evaluate and compare the clinical radiographic and biochemical parameters before and after treatment between the two groups.
研究设计
- 研究类型
- Interventional
- 分配方式
- Coin toss, Lottery, toss of dice, shuffling cards etc
- 盲法
- Participant and Outcome Assessor Blinded
入排标准
- 年龄范围
- 30.00 Year(s) 至 60.00 Year(s)（—）
- 性别
- All
入选标准
- •patients with minimum of 20 teeth excluding 3rd molars should be present patients diagnosed with stage III grade A periodontitis patients with vertical defect measuring greater than or equal to 3mm patient with good general health.
排除标准
- •Individuals with a history of systemic disease such as diabetes mellitus, hypertension, thyroid disorders, etc Pregnant or lactating women Patients with a history of regular antiinflammatory medication for past 3 months Former or current smokers and alcoholics Patients Allergic to aspirin or erythropoietin Patients with a history of usage of antibiotics or immunosuppressant medication within 6 months before start of study Patients with the history of periodontal treatment within the 6 months before the start of study.
结局指标
主要结局
radiographic parameter of vertical defect on CBCT Biochemical parameter of assessing the BMP2 levels
时间窗: base line | 6 months
次要结局
- gingival index(loe and silness 1963)(plaque index(silness and loe 1964))
研究者
DR ASMA ANJUM I
Bangalore Institute of Dental Sciences
研究点 (1)
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