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临床试验/NCT05723965
NCT05723965已完成不适用

Using CNN Image Recognition to Predict Rectal Cancer Outcomes

Taichung Veterans General Hospital1 个研究点 分布在 1 个国家目标入组 720 人开始时间: 2010年10月1日最近更新:
适应症

试验速览

阶段
不适用
状态
已完成
入组人数
720
试验地点
1
主要终点
accuracy of artificial intelligence with experienced physician

研究概览

简要总结

Investigator retrospective collect cases during 2010-2021 diagnosed as rectal adenocarcinoma with high quality CT images. Local advanced rectal cancer cases were labeled as "disease". Nor were defined " normal".

Using artificial intelligence CNN on jupyter notebook with open phyton code to train and develop models capable to recognizing local advanced rectal cancer. Modify the phyton code for better predict rate and help physician to quickly evaluate disease severity for fresh rectal cancer cases.

详细描述

From 2010.10.1~2021.12.31, rectal cancer patients with cT3-4 lesion was included. Collect high quality CT images with DICOM files in tumor segment. cT1-2, low rectal lesions, non-CRC cases were not included. Non-contrast and artificial defect images were also excluded. CT images were labeled as" diseased " when CRM were threatened (<2mm). All images were labeled according to judgment of 2 specialist. The data were separated into 2 parts. One for AI model training and testing, another for external validation. The training testing dataset was achieved by deep learning neural network and evaluating model accuracy performance. Then the model was applied into external validation dataset for real-world testing, evaluating coherent rate between AI and the Dr. decision. Furthermore, to see the cancer survival outcomes according to AI model prediction results.

研究设计

研究类型
Observational
观察模型
Case Control
时间视角
Retrospective

入排标准

年龄范围
20 Years 至 100 Years(Adult, Older Adult)
性别
All
接受健康志愿者

入选标准

  • clinical staging T3-4 with high quality CT images.

排除标准

  • not primary malignancy lesion
  • not localizing rectum
  • T1-2 lesion
  • non contrast or poor quality images

结局指标

主要结局

accuracy of artificial intelligence with experienced physician

时间窗: 1 week after images done.

accuracy between artificial intelligence and experienced physician

次要结局

  • real life survival outcome of diagnosis by artificial intelligence.(5 years after diagnosed)

研究者

申办方类型
Other
责任方
Sponsor

研究点 (1)

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