Feasibility of Dried Blood Spot (DBS) based screeningmethod to establish the seroprevalence of Epstein-Barr-Virus (EBV) in a large population of young adults
Recruiting
- Conditions
- B27Infectious mononucleosis
- Registration Number
- DRKS00033090
- Lead Sponsor
- Abteilung für Infektions- und Tropenmedizin, LMU Klinikum, LMU München
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- All
- Target Recruitment
- 3000
Inclusion Criteria
Completion of Informed Consent Form
Exclusion Criteria
1. Diseases and conditions that impede an Informed Consent
2. Insufficient command of the German language to a degree that impedes
Informed Consent
Study & Design
- Study Type
- observational
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method To test the feasibility of a DBS-based screening and recruitment strategy for future EBV-studies.
- Secondary Outcome Measures
Name Time Method 1. Using a commercially available assay which detects EBV-specific antibodies in serum samples and evaluate if it can measure antibodies in a comparable manner in a different specimen, namely eluted DBS so that it can be used for epidemiological purposes<br><br>2. Assess the responsiveness of volunteers in a campaign with filter paper cards sent out via mail for blood self-collection<br><br>3. Establishment and testing of a simple, reliable and cost-effective screening method to identify EBV negative and positive individuals in the population<br><br>4. Estimate the EBV seroprevalence in a population of 18-25 years old individuals and ask for their general willingness to participate in potential future EBV research and studies.