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临床试验/CTRI/2020/02/023098
CTRI/2020/02/023098已完成不适用

The effect of specific nasal breathing techniques on intra-ocular pressure.

Kasturba Medical College Manipal1 个研究点 分布在 1 个国家目标入组 164 人开始时间: 2020年5月2日最近更新:

试验速览

阶段
不适用
状态
已完成
入组人数
164
试验地点
1
主要终点
Changes in the intra-ocular pressure following specific nasal breathing techniques.

研究概览

简要总结

It has been studied that, there is high prevalence of Sleep Disordered breathing in patients with Primary Open Angle Glaucoma. Sleep disordered breathing is characterized by persistent snoring, upper airway resistance syndrome, and obstructive sleep apnea syndrome. Glaucoma is the condition of the eyes where in  most cases are due to raised intra-ocular pressure. As both these entities seem to be co-related, this study is to determine if specific nasal breathing techniques affects the intra-ocular pressure. Glaucoma is the most common cause of irreversible blindness worldwide. The only therapeutic approach accepted till now is directed towards lowering the intra-ocular pressure (IOP) either by medical, laser or surgical techniques. In addition to these methods, there is a need for evaluating non-pharmacological and non- surgical methods for lowering the IOP. It has been reported that unilateral breathing affects the autonomic nervous system, which in turn affects the IOP. A similar breathing exercise is practiced by many in our country as “Pranayamaâ€. We intend to study the effects of this form of specific nasal breathing technique on the intra-ocular pressure.

研究设计

研究类型
Interventional
分配方式
Stratified randomization
盲法
Investigator Blinded

入排标准

年龄范围
18.00 Year(s) 至 75.00 Year(s)(—)
性别
All

入选标准

  • Subjects coming to the Ophthalmology OPD, Kasturba Hospital, Manipal, as patients or by standers.

排除标准

  • Patients with following are excluded- participants with shallow anterior chamber depth, k/c/o angle closure suspect or angle closure glaucoma, participants already on anti-glaucoma medications, participants who have consumed 1 liter or more water in last one hour, patients who are k/c/o or giving h/o gross deviated nasal septum, nasal polyps, any other nasal obstruction, allergic or non-allergic rhinitis, URTI, LRTI, COPD or any other significant respiratory disorder, hypertensive patients on beta-blockers or any other drugs affecting the autonomic nervous system, CVS disorders, ANS disorders like orthostatic hypotension, postural orthostatic tachycardia syndrome.

结局指标

主要结局

Changes in the intra-ocular pressure following specific nasal breathing techniques.

时间窗: 5 mins

次要结局

  • blood pressure variation following specific nasal breathing techniques(5 mins)

研究者

申办方类型
Private medical college

研究点 (1)

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