Progranulin induces autophagy disorder in type 2 diabetic nephropathy

Completed

• Conditions: Diabetic nephropathy; Urological and Genital Diseases

• Registration Number: ISRCTN18100534
• Lead Sponsor: ational Natural Science Foundation of China

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Start: 2017-02-03
• Last Update Posted: 27 February 2017

Recruitment & Eligibility

• Status: Completed
• Sex: All
• Target Recruitment: 154

Inclusion Criteria

Patients:
1. Aged between 20 and 80 years old
2. Diagnosed with type 2 diabetes mellitus

Controls:
1. Aged between 32 and 72 years
2. Normal glucose control

Exclusion Criteria

1. Past history of malignancy
2. Degenerative disease of the nervous system
3. Diabetic macrovascular complications
4. Other endocrine diseases which affect glucose metabolism and lipid metabolism
5. Chronic hepatitis
6. Primary kidney disease
7. Recent inflammatory disease
8. Acute trauma
9. Taking thiazolidinedione drugs in the previous 3 weeks
10. Pregnancy
11. History of drug abuse.

Study & Design

• Study Type: Observational
• Study Design: Not specified