EUCTR2004-003825-29-GB进行中（未招募）不适用
MAGNET - a randomised placebo controlled trial of the use of nebulised magnesium sulphate in moderate/severe acute asthma in childhood - MAGNET
Cardiff and Vale NHS Trust0 个研究点目标入组 20 人开始时间: 2005年5月6日最近更新:
适应症
试验速览
- 阶段
- 不适用
- 状态
- 进行中（未招募）
- 发起方
- 入组人数
- 20
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Interventional clinical trial of medicinal product
入排标准
- 性别
- All
入选标准
- •. Severe asthma will be defined as per the BTS /SIGN guideline. For children 5 years and older severe asthma is based on one of the following criteria being met 1) oxygen saturations less than 93% while breathing room air 2) Peak expiratory flow (PEF) less than 50% best or predicted 3) Heart rate greater than 120/min 4) Respiratory rate greater than 30/min 5) Use of accessory neck muscles. For children aged 2-5 years of age, severe asthma is based on one of the following criteria being met 1) oxygen saturations less than 93% while breathing room air 2) Too breathless to talk or eat 3) Heart rate greater than 130/min 4) Respiratory rate greater than 50/min 5) Use of accessory neck muscles.
- •Management will be as per the guideline with inhaled (or nebulised) ß2 agonists, nebulised ipratropium and systemic corticosteroids. After 20 minutes of therapy, all children will have their oxygen saturations measured while breathing room air. All children with oxygen saturations of less than 93% will be invited into the study.
- •Are the trial subjects under 18? yes
- •Number of subjects for this age range:
- •F.1.2 Adults (18-64 years) no
- •F.1.2.1 Number of subjects for this age range
- •F.1.3 Elderly (>=65 years) no
- •F.1.3.1 Number of subjects for this age range
排除标准
- •Coexisting respiratory disease such as cystic fibrosis, chronic lung disease of prematurity, severe renal disease, severe liver disease, known to be pregnant.
研究者
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