Risk of Falling in Chronic Kidney Disease 5
- Conditions
- Stage 5 Chronic Kidney Disease
- Registration Number
- NCT02392299
- Lead Sponsor
- Queen Margaret University
- Brief Summary
The purpose of this study is to explore the relative importance of the frailty and cardiovascular function as potential exercise-modifiable risk factors for falling in patients receiving haemodialysis.
- Detailed Description
Falls and fall-related injuries in elderly people are common worldwide, and ageing populations will further raise the burden and costs. Within the UK, falls have become a major government target, as they have been responsible for increased injuries and hospital admissions in elderly people.
The fall rate amongst patients on haemodialysis (HD) is much greater than in the general population. There are many well established risk factors for falling, many of which are commonly present in patients on HD, including severe loss of muscle mass, high levels of inactivity, co-existing medical conditions and a high number of medications.
Nonetheless, the main cause of health complications and death in Chronic Kidney Disease (CKD) is due to cardiovascular disease. Cardiovascular disease may result in suboptimal regulation of blood pressure and heart rate during exercise, dialysis therapy, body transfers, and general activities of daily living. Associated symptoms such as dizziness, generalised fatigue, and muscular weakness, are commonly reported and may further predispose patients on HD to balance deficits and falls.
Despite the evidence of high falls rates in patients on HD and the growing number of elderly patients, falls and their associated risk factors have received little research attention.
The aim of this study therefore is explore the relative importance of selected exercise-modifiable risk factors for falling amongst patients on HD.
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- All
- Target Recruitment
- 93
- 18 years old
- Able to write/speak fluent English
- Stable dialysis
- Unstable dialysis and medication treatment
- Lower limb amputees without prothesis
- Unstable cardiac condition
- Suspected or known aneurysm
- Clinically severe left ventricular outflow obstruction
- Critical mitral stenosis
- Critical proximal coronary artery stenosis
- Critical cerebrovascular stenosis
- Pregnancy
- Severe cognitive impairment
Study & Design
- Study Type
- OBSERVATIONAL
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Falls incidence One year
- Secondary Outcome Measures
Name Time Method Frailty components baseline muscle strength, balance, gait speed, body composition
Trial Locations
- Locations (2)
Monklands Renal Unit
🇬🇧Airdrie, United Kingdom
Renal Unit
🇬🇧Falkirk, United Kingdom