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临床试验/TCTR20240516001
TCTR20240516001已完成1 期

Efficacy of Aloe vera toothpaste during active periodontal treatment: A clinical study

the National Science and Technology Development Agency under the Ministry of Science and Technology, Thailand.0 个研究点目标入组 54 人开始时间: 2024年5月16日最近更新:
适应症

试验速览

阶段
1 期
状态
已完成
发起方
入组人数
54

研究概览

简要总结

Aloe vera toothpaste significantly decreased gingival bleeding, probing depth, and clinical attachment level in periodontitis patients during active periodontal treatment.

研究设计

研究类型
Interventional

入排标准

年龄范围
20 Years 至 70 Years(—)
性别
All

入选标准

  • The subjects were required to
  • 1. Have at least 4 permanent teeth with periodontal pocket depth greater than 4 mm along with radiographic alveolar bone destruction
  • 2. Have full mouth plaque score more than 40 percent
  • 3. Exhibit bleeding on probing more than 30 percent
  • 4. Be in the age range of 20 to 70 years
  • 5. Provide informed consent

排除标准

  • The participants who
  • 1. Had been diagnosed as dental plaque induced gingivitis or nonplaque induced gingival lesions
  • 2. Had nonsurgical periodontal treatment in the preceding 12 months,
  • 3. Had orthodontic treatment within 12 weeks
  • 4. Had periodontal surgery in the preceding 12 weeks
  • 5. Had ongoing treatment with antimicrobials and/or anti-inflammatory medication
  • 6. Had been pregnancy or lactation
  • 7. Had been smoking or alcohol abuse
  • 8. Had a history of an allergic reaction to the toothpastes

研究者

发起方
the National Science and Technology Development Agency under the Ministry of Science and Technology, Thailand.

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