Detection of Subclinical Enthesitis by Ultrasonography in Psoriasis Patients With Psoriasis and Controls: by Ultrasonography; Incidence of Psoriatic Arthritis During Within One 1 Year
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 61
- 试验地点
- 1
- 主要终点
- Detection of Subclinical Enthesitis by Ultrasonography in Psoriasis Patients with Psoriasis and Controls: by Ultrasonography; Incidence of Psoriatic Arthritis During Within One 1 Year
研究概览
简要总结
Detection of subclinical enthesitis by ultrasonography
详细描述
A total of 30 patients with psoriasis and 30 age-matched healthy controls, all without musculoskeletal diseases, will be recruited. They will undergo dermatological assessment and a blinded ultrasound (US) evaluation. Clinical assessment included demographics, severity of psoriasis and musculoskeletal clinical examination. Evaluation consisted of the detection of grey scale (GS) enthesitis and Power Doppler signal in enthesis areas. The Madrid Sonography Enthesitis Index (MASEI) scoring system was used to quantify the extent of sonographic entheseal abnormalities.
研究设计
- 研究类型
- Observational
- 观察模型
- Case Control
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •Age≥18years
- •Patients with psoriasis without musculoskeletal symptoms
- •Healthy controls
- •No joint involvement and no clinical symptoms and signs of enthesitis and synovitis
排除标准
- •Have history of gout or arthritis or peripheral neurological disease of lower extremity.
- •Have history of trauma and intensive sport activity in last 2 weeks.
- •Have received any systemic therapy (i.e. DMARD, NSAIDs, corticosteroids, immunosuppressants, retinoids or biological agents) in 3 months
- •Pregnant or breast-feeding
结局指标
主要结局
Detection of Subclinical Enthesitis by Ultrasonography in Psoriasis Patients with Psoriasis and Controls: by Ultrasonography; Incidence of Psoriatic Arthritis During Within One 1 Year
时间窗: 1 year.
Incidence of subclinical enthesitis,To investigate the incidence of subclinical enthesitis in patients with psoriasis
次要结局
- Number of participants with Risk factors of subclinical enthesitis(1 year)
研究者
Duygu Karamanlıoğlu
Principal Investigator
Fatih Sultan Mehmet Training and Research Hospital