Does Benign Prostatic Obstruction Cause Hypertension?
- Conditions
- Prostatic HyperplasiaHypertension
- Registration Number
- NCT02347436
- Lead Sponsor
- St. Olavs Hospital
- Brief Summary
The known correlation between benign prostatic hypertrophy (BPH) and hypertension could be explained by 3 theoretical pathway models. Whether hypertension causes BPH, BPH causes hypertension or the two are caused by a common factor is currently unknown.
In this study it will be investigated whether hypertension is due to the direct effects of infravesical obstruction to urinary outflow in patients with benign prostatic hyperplasia. The approach will be blood pressure measurement in patients who will have a resection of the prostate.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- Male
- Target Recruitment
- 20
- Listed for inguinal hernia repair or hydrocele repair or transurethral resection of the prostate
- signed informed consent
- Treatment with antihypertensive medication that has been started within 3 months of inclusion.
- Treatment with antihypertensive medication that has been started after inclusion and before final blood pressure measurements have been obtained 6 months after operation.
- Any reason that the investigator deems that the participant will not comply with follow-up.
Study & Design
- Study Type
- OBSERVATIONAL
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method change in blood pressure 7,5 months one measurement 6 weeks pre-surgery, and ambulatory measurement during 6 months post-surgery
- Secondary Outcome Measures
Name Time Method prostate symptom severity assessed by 'International prostate severity score' (questionnaire) 7,5 months assessed by 'International prostate severity score' (questionnaire)
Trial Locations
- Locations (1)
St Olavs Hospital, Department of Urology
🇳🇴Trondheim, Norway
St Olavs Hospital, Department of Urology🇳🇴Trondheim, Norway