Corneal safety and stability in cases of Small incision lenticule extraction with collagen cross-linking (SMILE Xtra)
- Conditions
- Eye Diseases
- Registration Number
- PACTR201810577524718
- Lead Sponsor
- faculty of mediicne alexandria university
- Brief Summary
There was a significant difference between the 2 groups regarding UDVA, CDVA, and MRSE at 1 month. In SMILE Xtra group, 90 % of eyes had postoperative UDVA of 20/20 and 97 % had UDVA of 20/30 at 24 months. At 24 months, 26 eyes (87 %) vs. 25 eyes (84 %) were within + 0.50 D of attempted correction in SMILE Xtra and SMILE groups respectively. Regarding stability, both groups showed improvement of MRSE at 1st month postoperative and remained stable along the 24 months of follow up. CRF and corneal densitometry was higher in SMILE Xtra group along the whole follow up period (p = 0.001).
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete
- Sex
- All
- Target Recruitment
- 60
Patients > 18 years of age
Myopic error of > 6 D
Thinner cornea < 520 microns,
Abnormal corneal topography.
Associated corneal pathology,
Established keratoconus,
Corneal thickness < 450 microns
Hyperopia or mixed astigmatism.
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method
- Secondary Outcome Measures
Name Time Method