D AND BROWDER CHART VERSUS RULE-OF-NINES IN ASSESSMENT OF ADEQUACY OF FLUID RESUSCITATION IN PATIENTS ADMITTED WITH THERMAL BURNS AT THE BURNS UNIT OF KENYATTA NATIONAL HOSPITA
试验速览
- 阶段
- 未知
- 状态
- 已完成
- 入组人数
- 72
研究概览
简要总结
A total of 72 patients (36 per arm), presenting with thermal burns in the KNH Accident and Emergency Department, were recruited during the study period and allocated into the 2 groups: Group A for Lund and Browder Chart and Group B for Wallace Rule of Nines. The two groups were found to be statistically similar with regard to demographic and, injury and burn characteristics. There were no statistical differences between the two groups with regard to assessment of adequacy of fluid resuscitation: Serum lactate at 0 hours (p = .716), 8 hours (p = .876), and 24 hours (p = .164); base deficit at 0 hours (p = .314), 8 hours (p = .869), and 24 hours (p = .731); and urine output at 8 hours (p = 1.000), and at 24 hours (p = .693). The mortality rate within the first week of admission was 47.2% (34 patients). There were no statistical differences between the two groups in respect to mortality ?2 (1) = 0.223, p = .637, measures of adequacy of fluid resuscitation in the patients who died, and factors influencing mortality in burns patients (% TBSA, burn depth and presence of inhalational injury). The Lund and Browder group had a higher mean of %TBSA (52.5 ± 20.2 SD) than the Rule of Nines group (45.9 ± 20.4 SD), a not statistically significant difference of 6.6 (95% CI, -7.62 to 20.84), t (32) = 0.946, p = .351.The majority of the patients who died (44.1%) had mixed 2nd and 3rd degree burns. Of the patients who died, 88.2% had inhalational injury. In terms of the measures of adequacy of resuscitation in the patients who died, there were no significant differences between the two groups.
研究设计
- 研究类型
- Interventional
入排标准
- 年龄范围
- 0 Day(s) 至 1 Month(s)(—)
- 性别
- All
入选标准
- •1.Patients between 10 – 50 years old with TBSA 20% and above
- •2.Paediatric patients (< 10 years old) and Adult patients > 50 years old with TBSA 10% and above
- •3.Written informed consent or assent obtained from patient or next-of-kin
排除标准
- •1.No written informed consent or assent obtained from patient or next of kin
- •2.Patients with chemical burns
- •3.Patients with electrical burns
- •4.Patients who did not meet the criteria for fluid resuscitation as per the American Burn Association guidelines
- •5.Patients who presented >24 hours after the burn injury
- •6.Patients with known comorbidities affecting kidney function such as chronic renal failure and diabetes
