Investigation of TEST (Transcranial Electric Stimulation Therapy) for Chronic Pain

Not Applicable

Completed

• Conditions: Chronic Pain

• Registration Number: NCT05113563
• Lead Sponsor: New York State Psychiatric Institute

Brief Summary

The goal in this study is to investigate TEST (Transcranial Electric Stimulation Therapy) for chronic pain. It requires an inpatient stay on our research unit of about a month. The study is designed to address the cognitive and emotional aspects of chronic pain and other conditions that often accompany this disorder, such as major depression or drug use.

Detailed Description

This project proposes to investigate the feasibility of TEST in subjects with chronic pain. This will be an open-label study where subjects (n=12) are administered 8-10 sessions of TEST over 4 weeks. Measurements of pain, mood, and memory will be obtained before and after the sessions. The hypothesis is that TEST will be feasible and tolerable in this population.

Study Timeline

• Study First Submitted: 2021-10-28
• Study First Submitted QC: 2021-10-28
• Study First Posted: 2021-11-09
• Study Start: 2023-01-02
• Primary Completion: 2024-01-16
• Study Completion: 2024-01-17
• Results First Submitted: 2025-01-17
• Status Verified: 2025-03
• Results First Submitted QC: 2025-03-31
• Last Update Submitted: 2025-03-31
• Results First Posted: 2025-04-01
• Last Update Posted: 2025-04-01

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 6

Inclusion Criteria

1. adults (ages 22 to 60) who understand all procedures and have the ability to provide informed consent, with a score on the Mini-Mental Status Exam of at least 24;
2. participants experiencing chronic pain, with ongoing pain symptoms, and score on the Brief Pain Inventory of > 5 on question #3 (which asks about maximal pain in the past 24 hours) or > 5 on question #5 (which asks about average pain in the past 24 hours);
3. a diagnosis of chronic postoperative pain, low back pain, musculoskeletal pain, fibromyalgia, visceral pain or neuropathic pain, including complex regional pain syndrome or peripheral neuropathy;
4. no significant changes in pain medications for at least one month prior to study entry.

Exclusion Criteria

Not provided

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: SINGLE_GROUP

Primary Outcome Measures

Name	Time	Method
Feasibility Will be Assessed by the Percent of Participants Who Complete	4 weeks	Feasibility will be assessed by the percent of participants start study procedures and complete these

Trial Locations

Locations (1)

1051 Riverside Drive; 🇺🇸 New York, New York, United States