Risk reduction intervention of cardiovascular disease in China
- Conditions
- Cardiovascular diseasesCirculatory SystemCardiovascular disease, unspecified
- Registration Number
- ISRCTN58988083
- Lead Sponsor
- niversity of Leeds
- Brief Summary
2013 Protocol article in http://www.ncbi.nlm.nih.gov/pubmed/24160442 protocol 2017 Results article in https://pubmed.ncbi.nlm.nih.gov/28813512/ results (added 26/02/2021)
- Detailed Description
Not available
Recruitment & Eligibility
- Sex
- All
- Target Recruitment
- 28130
Inclusion criteria as of 29/07/2016:
Township hospitals:
1. Have family doctors who provide care according to the essential public health tasks requested by the government and who agree to follow the allocated treatment
2. Are willing to participate in the trial or pilot study
High CVD risk subjects:
1. Adults aged 50-74 years who have provided informed consent
2. Have been diagnosed as hypertension with a calculated 10-year CVD risk of 20% or higher, or have a recorded medical history of diabetes
3. Hold permanent residency in the study area
Previous inclusion criteria as of 06/12/2012:
Township hospitals:
1. Have family doctors who provide care according to the essential public health tasks requested by the government and who agree to follow the allocated treatment
2. Are willing to participate in the trial or pilot study
High CVD risk subjects:
1. Adults aged 60 years and above who have provided informed consent
2. Hold permanent residency in the study area
3. Have a calculated 10-year CVD risk of 20% or higher
4. Have a recorded medical history of diabetes, hyperlipidaemia, coronary heart disease, ischaemic or haemorrhagic cerebro-vascular disease, or peripheral vascular disease.
Previous inclusion criteria until 06/12/2012:
Township hospitals:
1. Located in rural Zhejiang
2. Have family doctors who provide care according to the essential public health tasks requested by the government and who agree to follow the allocated treatment
3. Are willing to participate in the trial or pilot study
High CVD risk subjects:
1. Adults aged 40-74 years who have provided informed consent
2. Hold permanent residency in the study area
3. Have a calculated 10-year CVD risk of 20% or higher, including those having a recorded medical history of hypertension (>140/90)
4. Diabetes, hyperlipidaemia, coronary heart disease, ischaemic or haemorrhagiccerebro-vascular disease, or peripheral vascular disease, or those without CVD symptoms.
Current exclusion criteria as of 06/12/2012:
1. People with known mental illnesses or other severe diseases or disabilities which mean they cannot communicate with township doctors well or regularly
2. Those not living in the community or will move away in the next two years
3. People who have shown serious adverse effects to the recommended drugs
4. Patients who decline to participate in the trial will be excluded
Previous exclusion criteria until 06/12/2012:
1. People with known mental illnesses or other severe diseases or disabilities which mean they cannot communicate with township doctors well or regularly
2. Those not living in the community or will move away in the next three years after recruitment
3. People who have shown serious adverse effects to the recommended drugs
4. Pregnant or breastfeeding women
5. Patients who decline to participate in the trial will be excluded
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method <br> Current primary outcome measure as of 06/12/2012:<br> The major CVD event rates of the residents in study areas<br><br> Previous primary outcome measure until 06/12/2012:<br> The percentage of end events in CVD morbidity and mortality<br>
- Secondary Outcome Measures
Name Time Method