The Application of Multimodal Ultrasound Imaging in Carpal Tunnel Syndrome

Not yet recruiting

• Conditions: Carpal Tunnel Syndrome (CTS)

• Registration Number: NCT06766370
• Lead Sponsor: The Affiliated Nanjing Drum Tower Hospital of Nanjing University Medical School

Brief Summary

The aim of this study is to explore the application value of multimodal ultrasound parameters in the diagnosis and treatment follow-up of Carpal Tunnel Syndrome.

Detailed Description

Not available

Study Timeline

• Study First Submitted: 2024-12-22
• Status Verified: 2025-01
• Study First Submitted QC: 2025-01-04
• Last Update Submitted: 2025-01-04
• Study First Posted: 2025-01-09
• Last Update Posted: 2025-01-09
• Study Start: 2025-02-01
• Primary Completion: 2025-12-01
• Study Completion: 2028-12-01

Recruitment & Eligibility

• Status: NOT_YET_RECRUITING
• Sex: All
• Target Recruitment: 40

Inclusion Criteria

1. Age between 18 and 70 years;
2. Presence of sensory abnormalities and motor dysfunction in the median nerve distribution area;
3. Positive Tinel's sign or Phalen's test;
4. Neurophysiological examination consistent with mild to moderate Carpal Tunnel Syndrome.-

Exclusion Criteria

1. Severe Carpal Tunnel Syndrome;
2. Concurrent rheumatic, metabolic, systemic, or other systemic diseases;
3. Concurrent cervical spondylosis or other peripheral neuropathies;
4. Wrist joint trauma, surgery, space-occupying lesions, or nerve itself with space-occupying lesions;
5. Concurrent malignant tumors or severe cardiopulmonary diseases;
6. History of previous wrist surgery or injections;
7. Pregnancy;
8. Allergy to corticosteroids or local anesthetics.-

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Boston Carpal Tunnel Syndrome Questionnaire ，BCTQ	1,3,6,12 months	The Boston Carpal Tunnel Score is a patient-reported questionnaire that examines symptom severity and overall functional status of patients with carpal tunnel syndrome. The Symptom Severity Scale (SSS) with 11 questions is scored on a Likert scale of 1-5 and the Functional Status Scale (FSS) with 8 questions is scored from 1-5 with 1 as no difficulty and 5 as difficult.The higher scores mean a worse outcome.

Secondary Outcome Measures

Name	Time	Method
the patient's sensory nerve conduction velocity (SNCV)	3,6,12months	SNCV in m/s
the patient's distal motor latency (DML).	3,6,12months	DML in ms