Ozurdex Treatment for macular edema associated with retinitis pigmentosa

Seoul National University Hospital0 个研究点目标入组 17 人开始时间: 待定最近更新: 2019年3月11日

适应症

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•Patients who are at least 18 years of age and had bilateral CME associated with RP are prospectively recruited. Diagnosis of RP was based on typical funduscopic finding of bilateral retinal degeneration, visual field constriction and/or ring scotoma, and markedly reduced rod response on standard electroretinography. To be included, RP patients are required to have macular cystic change as shown by spectral domain optical coherence tomography (OCT) with central subfield macular thickness (CSMT) of > 250 µm in both eyes.

•Key exclusion criteria are as follows: (1) advanced RP with foveal atrophic change or visual acuity of hand motion or less; (2) aphakia or pseudophakic eyes with zonule dehiscence or defective posterior capsule; (3) history of glaucoma or IOP elevation in response to steroid treatment in either eye; (4) history of vitrectomy; (5) diabetic retinopathy in either eye; (6) any active intraocular or periocular infection in either eye; (7) history of intravitreal or periocular steroids within 12 months; (8) history of intraocular surgery within 6 months; (9) any uncontrolled systemic disease.

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