Predictive Value of Inflammatory Indexes and CHA2DS2-VASc Score for LVT in ANT-MI With Left Ventricular Dysfunction

Completed

• Conditions: Left Ventricular Dysfunction; Left Ventricular Thrombus; Acute Anterior Myocardial Infarction
• Interventions: Other: inflammatory indexes and CHA2DS2-VASc score

• Registration Number: NCT04871126
• Lead Sponsor: Henan Provincial People's Hospital

Brief Summary

To investigate the predictive value of inflammatory indexes and CHA2DS2-VASc score for anterior myocardial infarction (ANT-MI) with left ventricular thrombus(LVT) (LVT).

Detailed Description

The clinical data were collected from 371consecutive patients with ANT-MI in our hospital from January 2014 to January 2021.As a result,totally 62 patients with LVT were selected as the experimental group and 186 patients with non-LVT as the control group .The observation indexes included baseline data, coronary angiography, disease course, laboratory examination and auxiliary examination.Patients with severe organic disease and having previous history of left ventricular aneurysm( LVA) and LVT were excluded.Data was analyzed by software SPSS 22.0 for statistical analysis,and the logistic regression model was established.A P\<0.05 was considered statistically significant, and the risk factors of LVT formation were retrospectively analyzed.

Study Timeline

• Study Start: 2014-01-01
• Primary Completion: 2021-01-01
• Study Completion: 2021-01-01
• Status Verified: 2021-04
• Study First Submitted: 2021-04-25
• Study First Submitted QC: 2021-04-28
• Last Update Submitted: 2021-04-28
• Study First Posted: 2021-05-04
• Last Update Posted: 2021-05-04

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 371

Inclusion Criteria

acute anterior myocardial infarction with left ventricular dysfunction

Exclusion Criteria

end-stage organic disease, thrombotic hematological disorders, previous anticoagulant use, and poor echogenicity

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Arm && Interventions

Group	Intervention	Description
LVT group	inflammatory indexes and CHA2DS2-VASc score	left ventricular thrombus in acute anterior myocardial infarction patients with left ventricular dysfunction
non-LVTgroup	inflammatory indexes and CHA2DS2-VASc score	acute anterior myocardial infarction patients with left ventricular dysfunction while without LVT

Primary Outcome Measures

Name	Time	Method
the predictive of the inflammatory indexes and CHA2DS2-VASc score in LVT	Day 1	the logistic regression model was established between the indexes and LVT