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临床试验/CTRI/2025/02/080667
CTRI/2025/02/080667尚未招募不适用

Prevalence and risk factors of cognitive impairment in chronic kidney disease patients

Vishnu Sarath1 个研究点 分布在 1 个国家目标入组 350 人开始时间: 2025年3月1日最近更新:

试验速览

阶段
不适用
状态
尚未招募
发起方
入组人数
350
试验地点
1
主要终点
Prevalence of cognitive impairment in chronic kidney disease patients using MoCA score

研究概览

简要总结

Cognitive impairment  has been reported from early stage chronic kidney disease patients. Prevalence of cognitive impairment in chronic kidney disease patients is 20% to 50% and up to 70 % in older patients on dialysis In everyday practice cognitive impairment in chronic kidney disease patients is still underdiagnosed, underreported and undertreated. This research project aims to address these issues. Patients will be included in the study as per inclusion criteria. MoCA test will be administered  for each patient and a score of 26 and above will be considered normal and any score below 26 will be considered as cognitive impairment. Total score of  18-25 will be considered as mild cognitive impairment, 10-17 as  moderate cognitive impairment and less than 10 as severe cognitive impairment. Variables included in the study age, gender, marital status, years of schooling schooling, alcohol use ,smoking, presence of comorbidities including hypertension, type 2 diabetes mellitus, hypothyroidism and cardiovascular disease. These variables will be analysed as possible risk factors for development of cognitive impairment

研究设计

研究类型
Observational

入排标准

年龄范围
18.00 Year(s) 至 99.00 Year(s)(—)
性别
All

入选标准

  • Patients who belong to chronic kidney disease stage3- stage 5 non dialysis patients.

排除标准

  • 1.Patients less than 18 years of age 2.Patients who are not giving consent to the study 3.Patients who had head injury, neurological disorders, encephalopathy.
  • 4.Patients taking psychiatric drugs and other drugs that interfere with cognitive functioning 5.Terminally ill patients.

结局指标

主要结局

Prevalence of cognitive impairment in chronic kidney disease patients using MoCA score

时间窗: Outcome will be assessed only at baseline when the patient is recruited.

次要结局

  • Risk factors for cognitive impairment in chronic kidney disease patients(outcome will be assessed only at baseline when the patient is recruited)

研究者

发起方
Vishnu Sarath
申办方类型
Other [self]
责任方
Principal Investigator
主要研究者

Vishnu Sarath

Kasturba Medical College, Manipal

研究点 (1)

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