NCT00811044WithdrawnNot Applicable
Regulation of Hepatic Insulin Extraction:Alterations of Insulin Secretion in Subjects With Genetic Variants That Determine Risk for Non-Insulin Dependant Diabetes Mellitus
Conditions
Trial Snapshot
- Phase
- Not Applicable
- Status
- Withdrawn
- Primary Endpoint
- Genes affecting the development of Type 2 diabetes will be identified
Study Overview
Brief Summary
- This study is in the area of Type 2 diabetes and genetics
- Healthy Volunteers and those with mild type 2 diabetes may be eligible to participate
- This study is searching for genes that may affect the body's processing/digestion of glucose/sugar
Detailed Description
This study is looking at the genetic influences of type 2 diabetes. It also is investigating the various gastric hormones including but not limited to: insulin, C-peptide, GIP, GLP, & Xenin.
Study Design
- Study Type
- Observational
- Observational Model
- Other
- Time Perspective
- Cross Sectional
Eligibility Criteria
- Ages
- 18 Years to 65 Years (Adult, Older Adult)
- Sex
- All
- Accepts Healthy Volunteers
- Yes
Inclusion Criteria
- •ages 18-65
- •non-diabetic
- •diabetes controlled with diet or with pills
- •no family history of diabetes
- •family history of type 2 diabetes
- •personal history of gestational diabetes
Exclusion Criteria
- •< 18 or > 65 years of age
- •medications that affect glucose (sugar) levels
- •kidney disease
- •liver disease
- •heart/cardiovascular disease
Outcomes
Primary Outcomes
Genes affecting the development of Type 2 diabetes will be identified
Time Frame: 1 year
Secondary Outcomes
- Any differences between genetic groups in the metabolism of glucose/sugar will be studied to the extent that the data allow(1 year)
Investigators
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