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Regulation of Hepatic Insulin Extraction

Withdrawn
Conditions
Diabetes
Registration Number
NCT00811044
Lead Sponsor
Washington University School of Medicine
Brief Summary

* This study is in the area of Type 2 diabetes and genetics

* Healthy Volunteers and those with mild type 2 diabetes may be eligible to participate

* This study is searching for genes that may affect the body's processing/digestion of glucose/sugar

Detailed Description

This study is looking at the genetic influences of type 2 diabetes. It also is investigating the various gastric hormones including but not limited to: insulin, C-peptide, GIP, GLP, \& Xenin.

Recruitment & Eligibility

Status
WITHDRAWN
Sex
All
Target Recruitment
Not specified
Inclusion Criteria
  • ages 18-65
  • non-diabetic
  • diabetes controlled with diet or with pills
  • no family history of diabetes
  • family history of type 2 diabetes
  • personal history of gestational diabetes
Exclusion Criteria
  • < 18 or > 65 years of age
  • medications that affect glucose (sugar) levels
  • kidney disease
  • liver disease
  • heart/cardiovascular disease

Study & Design

Study Type
OBSERVATIONAL
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
Genes affecting the development of Type 2 diabetes will be identified1 year
Secondary Outcome Measures
NameTimeMethod
Any differences between genetic groups in the metabolism of glucose/sugar will be studied to the extent that the data allow1 year
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